
Character Biosciences develops targeted therapies by identifying the genetic and molecular drivers of progressive polygenic diseases such as age-related macular degeneration. The company combines human genomics with longitudinal clinical records, retinal imaging, AI-enabled biomarker quantification, and machine learning to reclassify disease into genetically defined subtypes and pinpoint therapeutic targets. Character Bio operates as a precision medicine drug-discovery and development company that partners with ophthalmology clinics to build deeply phenotyped patient cohorts for research and trial enrollment. Its platform supports target discovery, patient selection, and the advancement of lead programs toward clinical trials. The approach aims to deliver more precise medicines by matching individual patients to therapies that address their specific disease drivers.

Character Biosciences develops targeted therapies by identifying the genetic and molecular drivers of progressive polygenic diseases such as age-related macular degeneration. The company combines human genomics with longitudinal clinical records, retinal imaging, AI-enabled biomarker quantification, and machine learning to reclassify disease into genetically defined subtypes and pinpoint therapeutic targets. Character Bio operates as a precision medicine drug-discovery and development company that partners with ophthalmology clinics to build deeply phenotyped patient cohorts for research and trial enrollment. Its platform supports target discovery, patient selection, and the advancement of lead programs toward clinical trials. The approach aims to deliver more precise medicines by matching individual patients to therapies that address their specific disease drivers.
About Character Biosciences Character Biosciences is a precision medicine company pioneering targeted therapies for polygenic diseases, with an initial focus on ophthalmology. Our patient data platform integrates genomics with deep, longitudinal clinical and imaging data, enabling us to uncover genetic drivers of disease progression, advance novel therapeutics, and define patient stratification strategies that improve clinical success.
Our interdisciplinary team, comprising experts in clinical science, data science, statistical genetics, computer vision, and drug discovery, utilizes this platform to determine genetic drivers of disease progression, advance novel therapeutics and define genetics-based patient stratification. Powered by our data platform, Character Bio is currently advancing two programs in Dry Age-related Macular Degeneration (AMD) with additional programs for other disease areas (e.g. Glaucoma) in earlier stages of discovery research.
Founded in 2018, Character has raised capital from leading investors at the intersection of healthcare and technology, including an oversubscribed $110+ million Series B in 2025 co-led by aMoon and Luma Group, with participation from Bausch + Lomb, Sanofi Ventures, Innovation Endeavors, Catalio Capital Management, S32, KdT Ventures, and Jefferson Life Sciences. We also maintain a multi-target drug discovery collaboration with Bausch + Lomb to develop innovative precision medicines for AMD.
Role : VP, CMC & Technical Operations
Reports to: Chief Scientific Officer
Department: R&D
Level: VP
Location : Hybrid - Jersey City, NJ/ Brisbane, CA/ Remote
The Opportunity The VP of CMC & Technical Operations will lead all Chemistry, Manufacturing, and Controls (CMC) activities at Character, with a current focus on early development and clinical supply. This leader will drive process and analytical development, regulatory CMC strategy, and CDMO oversight to enable IND/IMPD filings and ensure reliable supply for Phase 1-3 clinical trials. Operating in a lean biotech environment, the VP will combine strategic leadership with hands-on execution.
Key Responsibilities
Required Qualifications/ Experience
Compensation & Benefits The annual pay range for this full-time position is $280,000-$320,000 + equity + benefits
This salary range represents the expected base compensation for this role and may vary based on factors including experience, skills, and level.
Benefits include a competitive salary, strong equity incentives, medical, dental, vision, 401(k), an accrued paid time off policy. Character is committed to recruiting, developing, and supporting colleagues from all backgrounds. We embrace diversity, equity, and inclusion as an integral part of our culture.
EEO Statement Character Biosciences is an equal opportunity employer and is committed to building a diverse and inclusive workforce. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other legally protected status.
Work Authorization Applicants must be authorized to work in the United States.