
Seismic Therapeutic is a biotechnology company revolutionizing immunology drug discovery and development by integrating machine learning with biologics drug discovery elements such as structural biology, protein engineering, and translational immunology. The company operates a proprietary IMPACT platform to create optimized biologic therapies targeting dysregulated adaptive immunity for autoimmune diseases. With a strong leadership team and scientific founders, Seismic has a growing pipeline of best-in-class and first-in-class biologics, including clinical and preclinical candidates. Their approach emphasizes hyper-collaboration, inclusivity, and patient-centric innovation, positioning them as a leader in the immunology therapeutics space with significant traction in clinical trials and a robust investor syndicate.

Seismic Therapeutic is a biotechnology company revolutionizing immunology drug discovery and development by integrating machine learning with biologics drug discovery elements such as structural biology, protein engineering, and translational immunology. The company operates a proprietary IMPACT platform to create optimized biologic therapies targeting dysregulated adaptive immunity for autoimmune diseases. With a strong leadership team and scientific founders, Seismic has a growing pipeline of best-in-class and first-in-class biologics, including clinical and preclinical candidates. Their approach emphasizes hyper-collaboration, inclusivity, and patient-centric innovation, positioning them as a leader in the immunology therapeutics space with significant traction in clinical trials and a robust investor syndicate.
Stage: Clinical-stage immunology biotechnology company
Core technology: IMPACT platform — machine learning + structural biology for biologic design
Lead programs: Includes S-1117 (IgG protease) and S-4321 (PD-1 agonist); programs targeting IgE/allergic diseases
Funding: Raised a $121M Series B (Dec 4, 2023); total reported capital $222M
Founders include Jo Viney and Alan Crane; investors include Lightspeed, Bessemer, GV, Polaris, Amgen Ventures and others
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Autoimmune diseases, inflammatory diseases, allergic diseases
Biotechnology Research
$101,000,000
Launch financing; participants included founding investor Timothy A. Springer, Polaris Partners, GV, Boxer Capital, Samsara BioCapital, management and founders.
$121,000,000
Included new investors (Amgen Ventures, Codon Capital, Alexandria Venture Investments, Gaingels, GC&H) plus existing investors such as Lightspeed, Polaris, GV, Boxer Capital, Samsara BioCapital, and Timothy A. Springer; press release stated total capital raised $222M.
“Backed by a broad life-sciences investor syndicate including venture firms (Lightspeed, Bessemer, GV, Polaris) and strategic investors (Amgen Ventures, Alexandria Venture Investments) and notable individual investors.”
Company Description
Seismic Therapeutic™ is a biotechnology company leveraging machine learning to transform the discovery and development of novel medicines for immune-mediated diseases. The company's innovative IMPACT platform has delivered a pipeline of best-in-class and first-in-class biologics targeting dysregulated adaptive immunity to treat autoimmune and inflammatory diseases. Located in the Boston biotech hub of Watertown, MA, Seismic Therapeutic is supported by a strong network of leading life sciences investors. The company is dedicated to advancing breakthroughs in immunology to improve patient outcomes.
Role Description
This is a full-time, on-site role based in Watertown, MA, for a Senior Vice President or Vice President (SVP or VP) of Business Development. The successful candidate will lead and execute the company's business development strategy, identify and pursue new business opportunities, negotiate and structure contracts, and manage key partnerships. The role involves collaboration with internal teams to align business initiatives with organizational goals and oversight of sales and account management activities to drive company growth.
Apply via the link: https://seismictx.com/join-us/