Craif Inc.

Craif provides non‑invasive, urine‑based tests to detect multiple cancers at an earlier, more treatable stage. The company combines proprietary exosome collection with a curated microRNA database and machine‑learning algorithms to identify cancer‑specific signatures. Its flagship MySignal test screens for seven cancers, and Craif is developing an IVD pancreatic cancer test for high‑risk populations while running clinical validation in Japan and the U.S. Craif operates as a molecular diagnostics biotechnology company working with hospitals and research centers to commercialize tests and pursue regulatory approval and reimbursement in major markets.

BiotechnologyCancer DetectionEarly DiagnosisExosome TechnologyHealthcareLiquid BiopsyNanobiomarkersUrine Testcraif.com

Craif Inc.

BiotechnologyCancer DetectionEarly DiagnosisExosome TechnologyHealthcareLiquid BiopsyNanobiomarkersUrine Testcraif.com

HQIrvine, US

Team Size52

Open Jobs3

Total Funding$34M

Latest Fundraise11 months ago

Join the Team

Staff Engineer

On-SiteSan Diego, CA, US

On-Site • San Diego, CA, US

Teeming tracks opportunities at over 24,000 AI startups, then works with you to find (and land) the one you'll love.

AI Researcher

InternshipBerlin, DE

Internship • Berlin, DE

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Contract • London, GB

Backend Developer

Full-timeNiš, RS

Full-time • Niš, RS

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Part-timeJerusalem

Part-time • Jerusalem

AI Researcher

ContractBelgrade, RS

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ContractMunich, DE

Contract • Munich, DE

Company Description

Craif is a rapidly growing Japanese biotech startup with a commercially successful diagnostics business, generating over $1,400,000 in monthly revenue through partnerships with more than 2000 medical institutions in Japan. Leveraging our cutting-edge urine-based miRNA assay platform for early cancer detection, we are now expanding our operations to the United States.

We are seeking a dedicated and innovative Staff Engineer who is passionate about building both technologies and laboratory infrastructure from the ground up as we establish a new U.S. based research facility.

Position Summary

We are seeking a Staff Engineer, Software & Applications to lead the design, development, and evolution of our core laboratory systems and operational platforms. This role sits at the intersection of software engineering and laboratory excellence, with a strong emphasis on building AI-native applications and scalable architecture.

As a forward-deployed engineer, you will work closely with scientific teams in both the U.S. and Japan to translate complex lab workflows into intuitive, high-performance software. Your goal is to build a robust LIMS (Laboratory Information Management System) that not only supports our mission-critical diagnostics but also serves as a scalable platform for future external service expansion. This is a full-time, onsite position located in San Diego, CA.

Key Responsibilities

Lead the architecture, design, and implementation of our laboratory operations platform from the ground up, aiming for global-tier operational efficiency.
Develop AI-native applications using React and TypeScript, ensuring high-quality frontend and backend integration.
Drive UI/UX excellence by maintaining close communication with lab personnel, gathering direct feedback, and rapidly iterating on product usability.
Establish quality management systems and technical workflows required for CLIA certification.
Architect a scalable platform model based on our internal lab operations to enable future service expansion to external partners.
Serve as a technical leader and mentor, guiding engineers through design reviews and complex problem-solving.

Minimum Qualifications

Bachelor’s degree in Computer Science, Engineering, or equivalent practical experience.
8+ years of experience in software engineering roles.
Expert-level proficiency in React and TypeScript across the entire application stack.
Strong proficiency in one or more backend languages (e.g., Python, Java, Scala).
Proven experience in designing production-grade systems with a high focus on UI/UX and user-centric design.
Ability to work in a "forward-deployed" manner—directly engaging with end-users to define requirements.
Excellent verbal and written communication skills to bridge technical and scientific domains.
Ability to thrive in a fast-paced, rapidly evolving startup environment.

Preferred Qualifications

Experience with cloud platforms (AWS, GCP, or Azure).
Familiarity with containerization and orchestration (Docker, Kubernetes).
Experience supporting analytics, ML, or scientific data pipelines.
Background in regulated environments (e.g., healthcare, finance, diagnostics) is a plus.

Working Style

We are looking for an engineer who is:

Hands-on and proactive
Entrepreneurial, adaptable, and resourceful
Excited to build a new lab and diagnostic technologies from scratch
Mission-driven and collaborative

Salary Range

The estimated base salary range for this position is $125,000 – $160,000 (USD).