About Prima Mente Prima Mente’s goal is to deeply understand the brain, to protect the brain from neurological disease and enhance the brain in health. We do this by generating our own data, building brain foundation models, and translating discovery to real clinical and research impact.

Role focus - Foundation Models for Biology Architect, build, and scale our foundational AI infrastructure. You'll ensure our ML models are developed and deployed on highly performant, scalable, and reliable systems. Your expertise will enable rapid experimentation and seamless deployment of large-scale multi-omic models, empowering researchers to advance groundbreaking scientific discoveries.

• Architect, develop, and optimize robust ML training and inference infrastructure capable of supporting large-scale genomic foundation models.
• Design and implement scalable and efficient distributed computing platforms leveraging cloud (AWS/GCP/Azure) and HPC clusters.
• Develop highly automated, reproducible data pipelines and CI/CD workflows that accelerate model development, testing, and deployment.
• Performance-tune infrastructure and models, optimizing resource utilization (GPU/TPU) and significantly improving computation efficiency.
• Collaborate cross-functionally with ML researchers, bioinformaticians, and scientists to translate research needs into scalable engineering solutions.
• Ensure system reliability, robustness, and high availability, proactively implementing comprehensive monitoring, logging, and alerting solutions.
• Champion infrastructure-as-code (IaC) practices, promoting clarity, reproducibility, security, and auditability.

Expected Growth

• In 1 month you will be responsible for running initial experiments with state-of-the-art machine learning models, reviewing and implementing cutting-edge research papers, and optimizing existing code for efficiency and accuracy.
• In 3 months you’ll directly own and have created a prototype model architecture, demonstrated significant algorithmic improvements, and contributed to scaling methods for large-scale data ingestion and training.
• In 6 months you’ll have developed a high-performance version of a foundation model, implemented key algorithmic optimizations that boost scalability and throughput, and published internal benchmarks demonstrating significant research impact.

Who You Are

• Ambitious and Impact-Driven: You're inspired by working at the forefront of AI and biology, motivated by challenges that can significantly advance human health.
• Technical Excellence: You thrive in highly technical, complex environments and have a track record of turning cutting-edge research into robust production systems.
• Collaborative & Communicative: You excel at collaborating across disciplines, clearly articulating complex ideas, and driving alignment among research and engineering teams.

Ideal Experience

• Demonstrated ability to solve complex problems independently, with exceptional troubleshooting and system debugging skills.

Culture Insight What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands-on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous.

Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence.

We arrange our lives so we can work in person as much as possible.

Our Values