Helical

Helical is focused on providing open-source bio foundation models, particularly in the realm of single-cell analysis, enabling scientists to leverage advanced AI tools for their research. Their platform offers a community-driven approach, allowing users to fine-tune and integrate these models into their workflows, thereby enhancing research capabilities in the biological sciences. With a commitment to accessibility and collaboration, Helical positions itself as a key player in the AI for bio sector, catering to researchers and developers looking for innovative solutions.

AIBio Foundation ModelsOpen-sourceResearchSingle-cell Analysishelical-ai.com

Helical

AIBio Foundation ModelsOpen-sourceResearchSingle-cell Analysishelical-ai.com

HQLondon, GB

Team Size20

Open Jobs19

Total Funding$3M

Latest Fundraise2 years ago

TL;DR

What they do: Platform for Bio Foundation Models enabling in-silico experiments for drug discovery and R&D

HQ: Luxembourg

Stage / funding: Seed (closed Jun 28, 2024)

Founders: Mathieu Klop; Maxime Allard; Rick Schneider

Company Overview

Problem Domain

Drug discovery and pharmaceutical R&D using AI-driven in-silico experiments

Founded

2024

Industry

Biotechnology Research

Tech Stack

Cloudflare CDN

DNSSEC

Google Font API

HSTS

SPF

SSL

Funding Track Record

Seed- 2024-06-28

Reported seed round with seven investors

Investor Signal

“Has participation from early-stage investors and angel/backer set including Frst and named investors”

Founders

What we do

TL;DR

Company Overview

Funding Track Record

Founders

What we do

Helical

AIBio Foundation ModelsOpen-sourceResearchSingle-cell Analysishelical-ai.com

Helical

AIBio Foundation ModelsOpen-sourceResearchSingle-cell Analysishelical-ai.com

HQLondon, GB

Team Size20

Open Jobs19

Total Funding$3M

Latest Fundraise2 years ago

TL;DR

What they do: Platform for Bio Foundation Models enabling in-silico experiments for drug discovery and R&D

HQ: Luxembourg

Stage / funding: Seed (closed Jun 28, 2024)

Founders: Mathieu Klop; Maxime Allard; Rick Schneider

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Company Overview

Problem Domain

Drug discovery and pharmaceutical R&D using AI-driven in-silico experiments

Founded

2024

Industry

Biotechnology Research

Tech Stack

Cloudflare CDN

DNSSEC

Google Font API

HSTS

SPF

SSL

Funding Track Record

Seed- 2024-06-28

Reported seed round with seven investors

Investor Signal

“Has participation from early-stage investors and angel/backer set including Frst and named investors”

Founders

What we do

Related Companies

Company	HQ	Industry	Total Funding
LEGALFLY	🇧🇪Gent, BE	Data and AnalyticsDeepTechFinanceLegalProfessional ServicesSoftwareTransportation	$19M
Cambrium	🇩🇪Berlin, DE	BiotechnologyData and AnalyticsDeepTechHardwareManufacturingSoftware	$8M
Orakl Oncology	🇫🇷Paris, FR	BiotechnologyDeepTechHealth	$16M
Owkin	🇺🇸New York City, US	BiotechnologyData and AnalyticsDeepTechHealthSoftware	$304M
Merantix Momentum	🇩🇪Berlin, DE	Data and AnalyticsDeepTechInformation TechnologyProfessional Services	-

Join the Team

Senior Web Developer - Next.js + React

On-SiteLondon Area, GB

On-Site • London Area, GB

Join the Founding Team at Helical

📍 London or Luxembourg · Full-time📍

Helical is powering the in-silico labs for biology. Drug discovery still runs in wet labs: slow, expensive, and locked in physical trial-and-error. We’re changing that. Our platform makes Bio Foundation Models directly usable for discovery, enabling pharma teams to run millions of virtual experiments in days, not years.

That means you have a rare opportunity to help define how the next generation of drugs will be discovered. Today, leading pharma companies across the globe already use Helical. And we’re just getting started.

We’re a talent-dense team building a generation-defining company from Europe. We seek people who care deeply, ship fast, and want their work to change how medicine is made.

Teeming tracks opportunities at over 24,000 AI startups, then works with you to find (and land) the one you'll love.

Machine Learning Engineer

Full-timeUtrecht, NL

Full-time • Utrecht, NL

Backend Developer

Part-timeNiš, RS

Part-time • Niš, RS

Frontend Developer

ContractBerlin, DE

Contract • Berlin, DE

Software Engineer

InternshipCambridge, GB

Internship • Cambridge, GB

Software Engineer

ContractHaifa

Contract • Haifa

Technical Writer

Part-timeManchester, GB

Part-time • Manchester, GB

Join us on this journey as part of our founding team, you’ll help shape the in-silico labs of tomorrow.

Helical is pioneering the use of Bio Foundation Models to make biology computable and reshape how medicines are discovered. Our platform empowers pharma teams to apply these models in workflows such as target identification, biomarker discovery, patient stratification, perturbation prediction and more.

Helical raised over 3M€ in its Seed-funding round from leading VCs in France and the US as well as prominent Business Angels s.a. the CEO of HuggingFace, the CEO & CTO of Cohere, …

Join us to be part of the early-stage fast-growing founding team of Helical driving groundbreaking innovation and play a decisive role in contributing towards our ambitious goals, while being a part of an inspiring, collaborative and entrepreneurial culture in the heart of Europe.

Our github: https://github.com/helicalAI/helical/

Our Website: https://www.helical-ai.com/

We are seeking a Senior Web Developer with deep expertise in Nextjs + React to lead the architecture and development of our user-facing dashboard.

This isn’t just another CRUD app — the dashboard orchestrates long-running workflows , displays high-volume biological and model data , and interacts with systems like Airflow, MLflow, and Jupyter. The complexity is real — and elegant frontend design is what makes it usable.

If you are exceptional at Nextjs and React , understand how to structure component architectures that scale, and enjoy creating durable, well-designed UI systems, this is the role.

Responsibilities

Own and evolve the React + Next.js application architecture
Create robust UI patterns for complex workflows, logs, job status, and model results
Design state management strategies using tools like React Query / TanStack Query
Build clean and understandable abstractions around remote services (Airflow, MLflow, Jupyter)
Implement type-safe API interactions using tRPC and Zod .
Write testable UI code and use mocking effectively in unit and integration tests
Collaborate closely with product, backend, and ML engineers to shape user workflows

Requirements - Must-Have

4+ years of experience building production React applications
React — component architecture, hooks, memoization, rendering patterns, suspense
Next.js — routing, data loading strategies, server vs client rendering decisions
TypeScript — types that clarify code, not complicate it
State management at scale — e.g., React Query, Recoil, Zustand, MobX, etc.
Unit, integration, and E2E testing
Frameworks: such as Jest , React Testing Library , MSW , Cypress, Selenium, Playwright
API design — crafting clear, consistent interfaces and integrating complex backend data structures.
Data modeling / database schema design
Experience with modern TypeScript ORM frameworks such as Prisma or Drizzle ORM
Experience with authentication and authorization flows using AWS Amplify Gen 2 and Cognito
Implementing best practices in web security, including input validation, CSP headers, and safe API interaction.
Experience with component systems such as shadcn/ui
Deploying frontend services using Docker on AWS
Designing UI systems that remain clean as features expand

Experience with ML, scientific workflows, or data dashboards
Experience with Figma and a strong sense of UI/UX design, including layout systems, and usability principles.
Experience building stable UIs and designing APIs/systems around long-running or asynchronous backend operations
Familiarity with Airflow , MLflow , or Jupyter server APIs
Experience with Docker, Docker compose and containerized development environments
UI/UX sensitivity for scientific tools and data visualization