PAXAFE is a logistics orchestration and decision intelligence platform designed for cold chain and high-value cargo. It aims to reduce product loss, lower monitoring and intervention costs, optimize supply chain efficiency, and improve customer satisfaction. The platform offers solutions for operations, planning, and features an AI specialist called ATHENA. PAXAFE is data-agnostic, consolidating various data sources like LSP, IoT, and packaging data into a unified control tower. It helps in automated monitoring, risk analysis, lane qualification, dynamic lane risk analysis, and workflow automation. The company positions itself as the trust layer for temperature-controlled logistics, simplifying monitoring, minimizing alert noise, and enabling data-driven decisions.
PAXAFE is a logistics orchestration and decision intelligence platform designed for cold chain and high-value cargo. It aims to reduce product loss, lower monitoring and intervention costs, optimize supply chain efficiency, and improve customer satisfaction. The platform offers solutions for operations, planning, and features an AI specialist called ATHENA. PAXAFE is data-agnostic, consolidating various data sources like LSP, IoT, and packaging data into a unified control tower. It helps in automated monitoring, risk analysis, lane qualification, dynamic lane risk analysis, and workflow automation. The company positions itself as the trust layer for temperature-controlled logistics, simplifying monitoring, minimizing alert noise, and enabling data-driven decisions.
What they do: Logistics orchestration and decision-intelligence platform for cold chain and high-value cargo
Flagship products: CONTXT visibility platform and ATHENA recommendation engine
Founded: 2019
HQ / base: Indianapolis, Indiana
Recent financing: Series A announced May 7, 2024
Related Companies
Company
HQ
Industry
Total Funding
AeroCloud
🇬🇧Stockport, GB
Data and AnalyticsDeepTechHardwareInformation TechnologySoftwareTransportation
$14M
Orca AI
🇬🇧London, GB
DeepTechInformation TechnologyTransportation
$111M
ShipIn Systems
🇺🇸Newton, US
DeepTechHardwareSoftwareTransportation
$40M
Optimal Dynamics
🇺🇸New York City, US
DeepTechInformation TechnologyTransportation
$96M
Archetype AI
🇺🇸Palo Alto, US
Data and AnalyticsDeepTechInformation TechnologySoftware
$48M
Company Overview
Problem Domain
Cold chain and high-value cargo supply chain visibility, risk management and operational orchestration
Founded
2019
Industry
Software Development
Tech Stack
Cloudflare
Cloudflare CDN
Content Delivery Network
DMARC
DNSSEC
Font Awesome
Google Font API
LetsEncrypt
SSL by Default
Funding Track Record
Seed- 2021-05-12
Seed round announced May 12, 2021 (reported)
Series A- 2024-05-07
9000000 USD
Series A announced May 7, 2024 (lead investor reported as Framework Venture Partners; reported amount $9M)
Investor Signal
“Backed by a mix of venture and corporate investors including Framework Venture Partners, M12 (Microsofts venture fund), Ubiquity Ventures, Venture 53, Rosecliff Ventures and others”
Founders
What we do
Join the Team
Senior Technical Product Manager
RemoteUS
Remote • US
PAXAFE is a logistics orchestration & decision intelligence SaaS platform that helps Cold Chain planning, logistics, and quality teams consolidate their transportation data agnostically, digitize and automate product quality and lane qualification decisions, and operationalize prescriptive recommendations in the transportation network. Acting as the cold chain trust layer whose mission is to drive towards zero transportation waste, PAXAFE works with cold chain manufacturers and service providers to reduce product loss, improve operational efficiencies, and make more informed decisions in real-time. PAXAFE's vision is to become the backend intelligence infrastructure that powers every temperature, time, and value-sensitive shipment in the world. PAXAFE is backed by great VCs (Framework Venture Partners, Ubiquity Ventures, Venture53, RoseCliff Ventures, etc.) and CVCs (Microsoft M12, Northwestern Mutual, Greenlight Re)
The Role
As a
Senior Technical Product Manager
at PAXAFE, you will own and drive the development of PAXAFE's core product modules and AI-powered intelligence capabilities. You'll be responsible for evolving our 4 flagship modules — Lane Qualification, Data-Agnostic Visibility Command Center, Temperature Release, and Insights (Performance & Risk Monitoring) — while pioneering the integration of LLM and agentic workflows that transform how pharmaceutical supply chain teams interact with and act on supply chain intelligence.
Your primary customers will be pharmaceutical logistics teams, quality assurance managers, supply chain operations leaders, and cold chain specialists who rely on PAXAFE’s CONTXT platform to make critical decisions about temperature-sensitive shipments. You'll also work closely with PAXAFE's internal teams (Solutions Engineers, Data Scientists, ML Engineers, Customer Success) to ensure our AI capabilities deliver measurable value and seamless user experiences.
Key Responsibilities
Product Module Ownership & Development
Own the product strategy and roadmap for PAXAFE's 4 core modules: (1) Lane Qualification — carrier, packaging and route performance & risk evaluation and lane qualification workflows, (2) Data-Agnostic Visibility Command Center — operational dashboards and real-time shipment monitoring, (3) Temperature Release — intelligent temperature-release workflows and GxP compliance automation, (4) Insights — analytics & trend analysis, performance & risk monitoring
Define and prioritize features that deliver measurable customer value, focusing on minimizing scope and maximizing impact for pharmaceutical supply chain operations
LLM & Agentic Intelligence Integration
Pioneer the integration of Large Language Models (LLMs) and agentic AI workflows across PAXAFE's product modules to enable natural language queries, automated insights, and autonomous decision-making.
Design and ship AI-powered features such as: conversational interfaces for supply chain data ("Show me all shipments at risk in the Northeast corridor this week"), automated root cause analysis for temperature excursions, predictive recommendations for lane qualifications, intelligent alerting that surfaces the right information at the right time, and AI-generated performance summaries.
Define agentic workflows that automate complex multi-step processes: autonomous temperature-release decisions based on contextualized data and compliance rules, proactive risk mitigation actions triggered by predictive models, automated compliance documentation generation, intelligent alert routing and escalation, and self-healing integration workflows.
Partner with data science and ML teams to leverage PAXAFE's semantic data layer and ontology as the foundation for accurate, context-aware LLM responses and agent actions.
Cross-Functional Leadership & Execution
Work closely with Solutions Engineers to understand implementation challenges and ensure product features reduce integration complexity and accelerate customer time-to-value.
Collaborate with Design to create intuitive, consumer-grade user experiences for complex pharmaceutical supply chain workflows — making AI-powered insights accessible and actionable for users of varying technical backgrounds.
Partner with Engineering to translate product requirements into scalable technical solutions, balancing innovation with delivery speed and system reliability.
Coordinate with Data Science and ML teams to ensure model outputs are properly integrated into product experiences and that feedback loops improve model performance over time.
Document product requirements, user stories, AI model behaviors, and integration patterns to enable consistency and scalability across customer deployments.
Who We're Looking For
Experience
5+ years in product management (or related technical role), with at least 2 years building AI/ML-powered B2B/SaaS products or data-intensive applications.
Proven track record shipping highly successful and innovative products with your fingerprints all over them — and you're deeply proud of what you've accomplished. History of successfully launching and iterating on SaaS and/or B2B products.
Strong technical fluency with AI/ML concepts, LLMs, agentic workflows, and their practical applications in enterprise software. You don't need to write production code, but you can hold your own in technical conversations with data scientists and ML engineers.
Bonus Qualifications
Experience in pharmaceutical logistics, cold chain management, life sciences supply chain, or GxP-regulated environments.
Familiarity with IoT device integration, telemetry processing, and real-time data streaming architectures.
Knowledge of temperature-controlled logistics, thermal packaging, temperature excursion management, or pharmaceutical quality requirements (GDP, GMP compliance).
Experience with Supabase, PostgreSQL, or similar data infrastructure.
Hands-on experience with prompt engineering, RAG architectures, or building LLM-powered applications.
Why You'll Love Working Here
High-impact mission: Every project directly supports safe, compliant delivery of the world’s most important products worldwide (e.g. vaccines, life-saving therapies, food, etc.)
PAXAFE has entered an exciting growth phase, which provides for and requiresa great deal of autonomy & leadership at every role & every level
Ready to build the future of AI-powered pharmaceutical supply chain intelligence?
If you're ready to join a company that's pioneering LLM and agentic AI applications in pharmaceutical cold chain logistics — creating products that save lives while pushing the boundaries of what's possible with AI — then we want to hear from you! Apply today and let's build this together.
Use the link here to apply: https://ats.rippling.com/paxafe/jobs/711cd7e2-245a-442c-8395-1526cdc7e454
Teeming tracks opportunities at over 24,000 AI startups, then works with you to find (and land) the one you'll love.
Technical Writer
InternshipLondon, GB
Internship • London, GB
Backend Developer
InternshipTel Aviv
Internship • Tel Aviv
Technical Writer
ContractAustin, US
Contract • Austin, US
Mobile Developer
ContractHaifa
Contract • Haifa
Mobile Developer
Part-timeBelgrade, RS
Part-time • Belgrade, RS
Machine Learning Engineer
Part-timeRotterdam, NL
Part-time • Rotterdam, NL
Gather insights through direct customer engagement with pharmaceutical logistics teams, QA managers, and supply chain operations to understand workflows, pain points, and decision-making processes.
Translate complex pharmaceutical logistics requirements (real-time visibility, GxP compliance, temperature excursions, carrier performance, lane qualification criteria) into intuitive product features that simplify rather than complicate user workflows.
Collaborate with engineering teams to deliver scalable, technically feasible solutions that process diverse data from IoT providers (Sensitech, ELPRO, Controlant, Tive) and 3PL systems (UPS, FedEx, DHL, World Courier, Kuehne+Nagel).
Balance the needs of multiple user personas across the 4 modules — operations teams monitoring shipments in real-time, QA teams making release decisions, analysts reviewing performance trends, and supply chain leaders qualifying new lanes.
Comfortable speaking directly with operational leadership at pharmaceutical companies to shape solutions, gather feedback, and ensure product-market fit.
Experience building products that leverage LLMs, conversational AI, or autonomous agent systems. You understand the capabilities and limitations of these technologies and know how to apply them to solve real business problems.
Prior experience collaborating with data science, ML engineering, software engineering, and design teams to ship products in a B2B/SaaS environment.
Customer obsessed. You take on complex product challenges and simplify them to avoid making them our users' and partners' problems.
Entrepreneurial experience building and leading products, including ownership and optimization of business performance metrics.
Understanding of pharmaceutical compliance frameworks (GDP, GMP) and their impact on product requirements and workflows.
Previous experience building analytics products, operational dashboards, real-time monitoring systems, or business intelligence tools.
AI innovation playground: Work at the cutting edge of LLM and agentic AI applications in enterprise B2B software. Shape how pharmaceutical companies leverage AI to transform their supply chains. You'll be building AI products that solve real problems, not demos.
Remote-first flexibility: Work from anywhere (Central / Eastern US preferred)
Cutting-edge tech stack: Work with the latest AI/ML technologies alongside modern infrastructure. Technologies include: LLMs & Agentic AI | Azure | Python | Prismatic | Supabase | PostgreSQL | LavinMQ | Inngest | IoT | shadcn | Linear | Figma.
Growth opportunity: Step into a foundational technical leadership role with direct visibility to PAXAFE's executive team and Fortune 500 pharmaceutical customers. Shape the product direction at a high-growth startup.
Comprehensive benefits: Competitive base salary, equity participation, five weeks PTO, and full healthcare coverage