
Probably Genetic helps people with unexplained symptoms get answers fast by combining an online symptom assessment with clinical-grade genetic testing. The company identifies likely rare-disease cases with ML and LLM-powered symptom checkers, conducts whole exome sequencing via at-home test kits with physician review, and delivers results alongside genetic counseling. It operates as a direct-to-consumer diagnostic service while offering a data and testing platform used by patient advocacy groups and drug developers. Probably Genetic partners with 50+ advocacy organizations, has served over 100,000 patients, and emphasizes CLIA/CAP compliance and HIPAA-aligned data privacy.

Probably Genetic helps people with unexplained symptoms get answers fast by combining an online symptom assessment with clinical-grade genetic testing. The company identifies likely rare-disease cases with ML and LLM-powered symptom checkers, conducts whole exome sequencing via at-home test kits with physician review, and delivers results alongside genetic counseling. It operates as a direct-to-consumer diagnostic service while offering a data and testing platform used by patient advocacy groups and drug developers. Probably Genetic partners with 50+ advocacy organizations, has served over 100,000 patients, and emphasizes CLIA/CAP compliance and HIPAA-aligned data privacy.
About Probably Genetic Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.
We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it.
Probably Genetic has raised multiple rounds of funding from Silicon Valley’s best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.
About The Role We are looking for a Senior Software Engineer who will contribute to the design and implementation of our AI-enabled patient experience, genetic sequencing workflows, and help enable the critical infrastructure needed to support a world-class patient intelligence platform.
What you will do
Who you are
We are looking for a few specific things that will help you succeed in this role:
Proven experience developing full-stack applications, with a back-end focus and a passion for shipping high quality code at velocity
Experience in a range of software languages and frameworks included in our tech stack:
Languages: Python (Django) and Typescript (React)
Tools/Infrastructure: PostgreSQL, AWS, Terraform, GitHub Actions
Experience designing and building scalable systems used by external users
Track-record of solving extremely difficult, ambiguous problems
Excellent communication skills with ability to can convey your ideals clearly to engineers and non-engineers alike!
Some things that are not required, but you will learn on the job:
As with all new hires at Probably Genetic, you will also need to be:
What We Offer At Probably Genetic
Probably Genetic is committed to fostering a welcoming and inclusive work environment for people of all genders, sexuality, ethnicity, socioeconomic background and life experiences. We urge candidates of all backgrounds to apply. If you require specific accommodations as you interview or consider working with us, please let us know.