We are looking for a passionate and dynamic hands-on scienti st to build Orakl's CRISPR and functional genomics capabilities from the ground up. Reporting directly to the Principal Scientist, you'll design and run gene-perturbation and drug screens in our patient-derived tumor organoids, generating the high-quality biological data that powers our AI predictive engine.

Must have

• PhD in molecular biology, cancer biology, biotechnology, or related field, ~1–5 years industry experience would be a plus.
• Proven proficiency with CRISPR gene editing in mammalian systems (ideally in organoids): gRNA design, MOI optimization, KO validation.
• Experience with both lentiviral-based and electroporation-based is preferred.
• Hands-on expertise in organoid culture.
• Knowledge of molecular biology techniques (RT PCR, qPCR/ddPCR, Western Blot, DNA and RNA isolation etc.) and flow cytometry/FACS.
• Exceptional wet-lab fundamentals: sterile technique, routine culture, molecular biology, cloning, assay development, QC.
• Demonstrated ability to independently plan, prioritize, and execute complex experimental pipelines with high quality and reproducibility.
• Strong analytical, quantitative data interpretation, and clear documentation/reporting skills.

Nice to have

• Experience with pooled/arrayed CRISPR screens or other functional genomics approaches.
• Experience with drug-response profiling in organoids (dose–response, time-course, combination assays) and high-throughput screening.
• Knowledge of programming e.g. Python
• Previous responsibility for managing CROs or academic collaborations.
• Experience mentoring junior scientists, lab technicians and/or establishing lab standards.
• Prior involvement in early-stage drug discovery or cross-functional oncology research.

Interested? Apply and we will be in touch!