Company Description Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through an innovative therapeutic modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic modality innovation in biotechnology.

Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.

THE ROLE We are seeking an experienced and motivated Senior Scientist in Medicinal Chemistry specializing in miniprotein and peptide drugs. The successful candidate will lead projects in designing, synthesizing, and optimizing novel miniprotein therapeutics called Synteins™. This role offers a unique opportunity to bring a new drug modality from early-stage research through to clinical development.

Key Responsibilities

• Independently plan, execute, interpret, and optimize Syntein structure-activity campaigns through direct, hands-on laboratory work.
• Implement modern peptide chemistry and conjugation methodologies to accelerate optimization of miniprotein drug development.
• Collaborate with cross-functional teams including computational chemistry, biology, and pharmacology to drive project success.
• Drive bench-side innovation, ensuring that ideas transition seamlessly from concept to reality
• Mentor and guide junior scientists, fostering a collaborative and dynamic laboratory environment.
• Contribute to patent applications and scientific publications, showcasing lab innovation.

Professional Experience & Qualifications

• Ph.D. in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or related field, with a minimum of 5 years of industry experience.
• Strong track record of laboratory-based innovation and problem-solving in drug discovery including optimization of affinity, selectivity, drug properties, and PK profile.
• Proven expertise in the hands-on peptide synthesis.
• Ability to lead and inspire a team of scientists in a dynamic research setting.
• Excellent communication skills for both technical and non-technical audiences.
• Able to work on-site and attend in-person meetings.

About Flagship Pioneering Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer . All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification . If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. The salary range for this role is $126,000 - $181,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc’s good faith estimate as of the date of publication and may be modified in the future.