About Escalante
Escalante is dedicated to enabling the next generation of biological insights. Our platform unlocks scalable, functional, single-molecule proteomics by combining cutting-edge molecular biology, protein biochemistry, and artificial intelligence. We want to build AI models that predict how cells respond to therapeutic perturbations. These models would transform biology and drug discovery, but require fundamentally new measurement technologies and datasets. To build these we rely on our people, our ambition, and our willingness to challenge the way science is done.
The Opportunity
As a senior research associate at Escalante you will work closely with an interdisciplinary group of scientists and engineers to develop the next generation of scalable single-molecule proteomics.This role is a wet-lab based position where you will work with our biology team to help develop high-throughput proteomics assays. Through this work you will directly contribute to our core platform and help guide Escalante’s trajectory.
This is a full-time on-site role in San Francisco, California.
Responsibilities
- Execute bacterial expression and protein purification using established protocols, with opportunities to refine and improve methods.
- Execute and troubleshoot standard molecular cloning protocols (Golden Gate assembly, site directed mutagenesis, etc).
- Characterize purified proteins using SDS-PAGE, Bradford assays, mass spec and other relevant techniques.
- Assist scientists in optimizing workflows and troubleshooting routine issues.
About You
- Bachelor’s degree in biology or related field, with approximately 4 years of industry experience.
- Hands-on experience in bacterial protein purification workflows with preference given to those with experience in both bacterial and mammalian protein purification workflows.
- Outstanding ability to record and communicate scientific work
Pluses
- Master’s degree in biochemistry or related field
- Experience with pooled library experiments and NGS workflows.
- Basic familiarity with Python programming
Compensation:
competitive salary + equity + benefits
Benefits Include:
Generous paid time off, 100% health coverage, employee stock option plan, paid parental leave, office snacks and beverages
Escalante is committed to equal employment opportunity regardless of race, color, ancestry, national origin, religion, sex, age, sexual orientation, gender identity and expression, marital status, disability, or veteran status. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
