
Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class AI-powered techbio platform. The platform integrates real-world patient data with advanced biology to create individualized patient tumor avatars that simulate drug responses, improving clinical trial success rates and patient recruitment. Orakl markets two AI-powered commercial products, O-Predict and O-Validate, which forecast patient responses and provide biological evidence for target validation, respectively. The company targets colorectal and pancreatic cancers, addressing major unmet medical needs, and aims to transform drug development by enabling better decision-making and strategic partnerships with pharmaceutical companies. Orakl has raised nearly €15 million in funding and is building a dedicated business team to support its growth and market entry.

Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class AI-powered techbio platform. The platform integrates real-world patient data with advanced biology to create individualized patient tumor avatars that simulate drug responses, improving clinical trial success rates and patient recruitment. Orakl markets two AI-powered commercial products, O-Predict and O-Validate, which forecast patient responses and provide biological evidence for target validation, respectively. The company targets colorectal and pancreatic cancers, addressing major unmet medical needs, and aims to transform drug development by enabling better decision-making and strategic partnerships with pharmaceutical companies. Orakl has raised nearly €15 million in funding and is building a dedicated business team to support its growth and market entry.
Founded: 2023 (spin‑out from Gustave Roussy)
Headquarters: Villejuif / Paris region, France
Focus: AI-powered precision oncology using patient-derived tumor avatars (organoids) and multimodal data
Products: O-Predict and O-Validate (AI commercial products)
Known funding: ≈ €14–15M across 2023–2024 (seed / pre-seed rounds)
Preclinical and clinical de-risking for oncology drug discovery and development, with initial tumor-type focus on colorectal and pancreatic cancers.
2023
Biotechnology Research
€3,000,000
Reported pre-seed/seed round
€11,000,000
Seed round with participation from multiple investors
“Singular; Bpifrance; Speedinvest; Verve Ventures; HCVC; SistaFund; Amazon Web Services”
| Company |
|---|
At Orakl Oncology , we are accelerating the development of oncology treatments. Today, fewer than 5% of new cancer drugs succeed in clinical trials. Clearly, new methods are needed. We combine cutting-edge biology and AI to build the next generation of insight platforms with the world’s largest cohort of patient tumor avatars. These avatars fuel our AI-powered predictive engine , helping to anticipate clinical trial outcomes, validate therapies, and uncover new drug candidates.
Our mission is simple yet ambitious: to who need them - and to make drug development smarter, faster, and more personalized. We collaborate with top hospitals, research institutes, and pharmaceutical companies worldwide. Backed by leading investors, we are a at the intersection of science and technology.
We are looking for a highly skilled technical profile who enjoys building new computational methods and turning them into reliable production tools . You will design, implement, and maintain computational biology methods based on multi-omics data. You will ensure that these methods are deployable on internal and external projects and robust at scale. You will work collaboratively with an interdisciplinary team of computational biologists, AI/ML experts, cell biologists, and oncologists to drive drug discovery in cancer.
This role is ideal for someone with an engineering background and a strong interest in biology, but any candidate who wants to build methods that scientists will use every day in production to advance cancer science is a strong fit.
Key Responsibilities
Minimal qualifications
Preferred qualifications
HR Call (15 minutes call) – An initial discussion to better understand your background, experiences, and motivations.
Technical Interview (45 minutes call) – A deep dive into your technical skills and expertise relevant to the role.
Technical Case (30 minutes presentation + discussion) - A case study or problem-solving exercise to assess your strategic thinking and analytical abilities. If possible this can be done in person.
Engineering Case (45-minutes presentation + discussion) - You will be presenting a piece of work you have previously worked on and which you are proud of. This will be in front of the relevant members of the Orakl Oncology team. If possible this can be done in person.
Founders Interview: As final step of our recruitment process, you will meet the founders of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values.