
Matterworks turns complex omics measurements into usable biological insights to speed research and development in life sciences. It does this via an AI-driven SaaS platform—including its Large Spectral Model (LSM) and Pyxis product—that ingests mass spectrometry and other metabolomics data and applies machine learning to standardize, interpret, and simulate metabolic environments. The platform emphasizes automation, cloud delivery, and scalability to make unstructured spectral and omics data broadly accessible to biotech teams. Typical users are biotechnology researchers and biomanufacturing groups seeking quantitative, real-time insights for experimental design and process optimization. Matterworks operates at the intersection of AI, metabolomics, and bioinformatics in a market focused on accelerating therapeutic R&D and manufacturing.

Matterworks turns complex omics measurements into usable biological insights to speed research and development in life sciences. It does this via an AI-driven SaaS platform—including its Large Spectral Model (LSM) and Pyxis product—that ingests mass spectrometry and other metabolomics data and applies machine learning to standardize, interpret, and simulate metabolic environments. The platform emphasizes automation, cloud delivery, and scalability to make unstructured spectral and omics data broadly accessible to biotech teams. Typical users are biotechnology researchers and biomanufacturing groups seeking quantitative, real-time insights for experimental design and process optimization. Matterworks operates at the intersection of AI, metabolomics, and bioinformatics in a market focused on accelerating therapeutic R&D and manufacturing.
What they do: AI-driven SaaS platform that applies self-supervised ML to mass spectrometry and metabolomics to produce actionable insights for life-science R&D
Headquarters: Somerville, Massachusetts
Founded: 2019
Notable products: Pyxis platform and Large Spectral Model (LSM)
Recent financing: Series A announced June 3, 2025 (multiple investors including Lewis & Clark Capital and OMX Ventures)
| Company |
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Metabolomics and mass spectrometry data interpretation for life-science R&D (discovery, toxicology, clinical development, biomanufacturing).
2019
Biotechnology Research
Series A announced on June 3, 2025; multiple participating investors reported
“Has participation from multiple institutional VCs including Lewis & Clark Capital, OMX Ventures, Germin8 Ventures, Pillar VC, Tarsadia Investments, Intermountain Ventures”
About Us At Matterworks we are building AI tools to extract insights from the ever-growing corpora of biological data and to unlock opportunities in therapeutic discovery, development, and manufacturing. We are building large-scale deep learning models of biological data to predict the phenotype and behavior of biological systems.
Position Overview As a Senior Machine Learning Scientist, you will be a core contributor to our deep learning systems, designing, building, and optimizing the neural network architectures that interpret complex mass spectrometry data. You will own significant model components and drive projects from experimentation through deployment. This role requires hands-on depth in deep learning and a passion for building high-quality, impactful models.
Key Responsibilities
Qualifications
Working at Matterworks Given the cross-disciplinary and innovative nature of our work, effective collaboration and communication are critical to our progress. We operate in a flexible hybrid model that accommodates both fully remote team members and those who work full-time from our Somerville, MA office. While some positions may require regular in-person presence for hands-on work or local collaboration, many roles can be performed remotely with team members distributed across various locations.
Compensation And Benefits Matterworks offers a competitive base salary, stock options, and benefits (health & dental, vision, long- and short-term disability, life insurance, 401k with company match). Employees enjoy a flexible work & unlimited time away policy, commuter benefits and parking, regular team meals and outings, and company support for continued education/coursework and conference participation.
Matterworks, Inc. is an equal opportunity employer. All candidates for employment at Matterworks are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other category protected by law.