
Dyno Therapeutics develops AI-powered gene therapy vectors to improve targeting and efficacy of gene treatments. The company uses machine learning and quantitative high-throughput in vivo experimentation to design novel adeno-associated virus (AAV) capsid proteins that target specific cell types. Dyno combines molecular biology, protein engineering, and computational models to optimize vector performance and manufacturability. It operates as a biotechnology partner to biopharmaceutical companies and research institutions, creating proprietary AAVs and collaborating through licensing and development agreements.

Dyno Therapeutics develops AI-powered gene therapy vectors to improve targeting and efficacy of gene treatments. The company uses machine learning and quantitative high-throughput in vivo experimentation to design novel adeno-associated virus (AAV) capsid proteins that target specific cell types. Dyno combines molecular biology, protein engineering, and computational models to optimize vector performance and manufacturability. It operates as a biotechnology partner to biopharmaceutical companies and research institutions, creating proprietary AAVs and collaborating through licensing and development agreements.
What they do: AI-driven design of AAV capsids and gene-delivery vectors for targeted gene therapies
Founded: 2018
Headquarters: Cambridge/Watertown, MA
Notable funding: $100M Series A led by Andreessen Horowitz (May 2021)
Gene therapy vector design and optimization
2018
Biotechnology Research
$100,000,000
May 6, 2021 Series A financing; participation from Casdin Capital, GV, Obvious Ventures, Lux Capital, and existing/founding investors including Polaris Partners, CRV, and KdT Ventures.
“Participation by top-tier biotech and deep-tech VC firms including Andreessen Horowitz, Casdin Capital, GV, Lux Capital, Polaris Partners, CRV, and KdT Ventures”
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The Role
We are seeking a Platform Infrastructure Sr. Engineer to build the foundational cloud infrastructure powering Dyno’s integrated platform for AI-driven protein design. As a Platform Infrastructure Engineer, you’ll work alongside senior engineers to design, implement, and scale reliable infrastructure for machine learning and Python services.
How You Will Contribute
As part of the Computational Platform team, you will help design, deploy, and maintain the core systems that make large-scale model training and serving possible. You’ll contribute directly to infrastructure improvements that increase platform reliability, developer velocity, and the performance of ML workloads across the company.
Required qualifications
Preferred qualifications
The Company
At Dyno Therapeutics, we are a forward-thinking team on a mission to build high-performance genetic technologies that transform patient lives. Our team unites world-class molecular biologists, protein engineers, software developers, data scientists, and machine learning experts—all working together to shape the future of gene therapy. Our culture is defined by three core values:
What You’ll Give:
What You’ll Get:
If you’re ready to push boundaries, build the future, and thrive in a fast-moving, high-impact environment—we’d love to hear from you.