Kardigan

Kardigan develops personalized cardiovascular medicines intended to move patients beyond symptom management toward functional cures. The company uses a proprietary Cardiac Intelligence R&D platform…

kardigan.bio

Kardigan

kardigan.bio

HQSouth San Francisco, US

Team Size145

Open Jobs29

Total Funding$554M

Latest Fundraise7 months ago

Join the Team

Senior Director, IT Business Partner – Medical & Commercial

On-SiteSouth San Francisco, CA, US

On-Site • South San Francisco, CA, US

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About Us Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Sr Director, IT Business Partner, Medical & Commercial

Department: Information Technology

Reports To: Head of IT Business Partner & Solution Delivery

Location: Princeton, New Jersey or South San Francisco, CA (Onsite 4 days per week Mon – Thurs)

Job Overview Kardigan is seeking an experienced, visionary and hands-on IT Business Partner, to align IT strategies with the dynamic needs of our Medical and Commercial organizations. This critical role will establish and lead a robust IT Business Partner framework tailored to the biopharmaceutical environment overseeing those functional areas and others, such as G&A, as needed. This role requires exceptional leadership, strategic thinking, and deep knowledge of IT systems in Medical, Commercial and G&A with specific expertise in Veeva.

Essential Duties And Responsibilities

Qualifications And Preferred Skills

Exact Compensation may vary based on skills, experience and location.

Pay range

$240,000 - $335,000 USD

IT Partnership Leadership: Serve as the primary IT liaison understanding the unique needs of the Medical and Commercial business domains and driving technology solutions that enhance operational efficiency and innovation. Supporting other domains such as G&A will needed for short-term.

IT Business Analysis: The role leads hands-on end‑to‑end business analysis activities across initiatives, partnering closely with stakeholders to understand processes, identify gaps, and translate business needs into clear, testable, and compliant requirements. This includes facilitating workshops, documenting AS‑IS and TO‑BE processes, and producing high‑quality artifacts such as business requirements, functional specifications, user stories, and acceptance criteria. The role ensures requirements are fully traceable across design, testing, and validation, aligned with GxP and regulatory expectations where necessary, and provide a strong foundation for compliant solution delivery and successful business outcomes.

Validated Systems Oversight: Ensure IT systems supporting critical functions (e.g., Medical, Commercial platforms) comply with regulatory requirements such as GxP, HIPAA, and data privacy, supporting the integrity and security of biopharmaceutical processes.

Strategic Alignment: Collaborate with functional leaders to define and prioritize IT initiatives that align with business goals, balancing short-term operational needs with long-term strategic objectives.

Digital Transformation: Drive digital innovation and transformation across the organization, leveraging emerging technologies to enhance productivity, optimize processes, and support global commercialization efforts.

System Implementation & Integration: Oversee the successful implementation and integration of IT systems across the supported business domains, ensuring seamless data flow and interoperability to support regulatory compliance and decision-making.

Compliance and Risk Management: Partner with Quality and Regulatory teams to ensure IT systems meet biopharma-specific compliance standards and are audit-ready. Manage risk assessments and implement safeguards to protect sensitive data and intellectual property.

Team Leadership: Build, mentor, and lead a high-performing team, fostering collaboration and ensuring effective support for all functional areas.

Program & Project Management: Lead complex and critical IT projects, including system implementations and upgrades, ensuring delivery within scope, budget, and timelines while maintaining compliance with regulatory requirements.

Stakeholder Collaboration: Develop strong relationships with senior leaders and stakeholders, providing strategic insights and recommendations that drive business performance.

Vendor Management: Oversee vendor relationships and contracts for systems ensuring cost efficiency and alignment with organizational needs.

AI & Data Competencies: The role enables AI and data‑driven capabilities across Medical, Commercial and other domains, as needed, by translating business needs into governed, compliant AI and analytics solutions, including generative AI and advanced reporting. This includes working with enterprise data lakes to support ingestion, curation, and use of regulated data, while partnering with various stakeholders to ensure data integrity, privacy, and inspection‑ready AI and data solutions.

Bachelor's degree in Computer Science, Business Administration, or a related field; advanced degree preferred.

12+ years of progressive IT experience, with at least 5 years in a leadership role partnering with business functions in a regulated environment.

Demonstrated success in aligning IT strategies with business objectives in Medical, Commercial and other domains such as G&A.

Strong knowledge of validated systems, enterprise applications such as Veeva suite, and digital transformation strategies relevant to the biopharmaceutical industry.

Experience in regulated environments, including GxP, HIPAA, GDPR/CCPA and data integrity standards.

Exceptional stakeholder management and communication skills, with the ability to influence and build consensus at all organizational levels.

Proven expertise in leading cross-functional IT initiatives and managing large-scale projects.

Strong problem-solving, decision-making, and analytical skills.

Experience in recruiting, mentoring, and building high-performing teams.

Expert‑level business analysis and requirements management capability

Ability to translate complex business needs into compliant technology solutions

Excellent written, verbal, and facilitation skills

Familiarity with Pharma platforms such as:

Veeva (CRM, Vault Medical, Vault Quality)

QMS and document management systems

Clinical, safety, and regulatory system integrations

Experience preparing for and supporting commercial launches from a technology system and data perspective.

Understanding of system integrations, data flows, data lake, analytics & reporting architecture

Strong Program and Project management skills

Strong collaboration skills with internal IT team and external partners