
Kardigan develops personalized cardiovascular medicines intended to move patients beyond symptom management toward functional cures. The company uses a proprietary Cardiac Intelligence R&D platform and AI-based analytics to identify biomarkers for safety, efficacy, and patient responder selection prior to human trials. Kardigan is a clinical-stage biopharmaceutical company that integrates biomarker-driven patient selection and data-driven trial design into its development programs. The company is building a portfolio of therapies that target underlying cardiovascular disease pathophysiology to address unmet needs in heart health.

Kardigan develops personalized cardiovascular medicines intended to move patients beyond symptom management toward functional cures. The company uses a proprietary Cardiac Intelligence R&D platform and AI-based analytics to identify biomarkers for safety, efficacy, and patient responder selection prior to human trials. Kardigan is a clinical-stage biopharmaceutical company that integrates biomarker-driven patient selection and data-driven trial design into its development programs. The company is building a portfolio of therapies that target underlying cardiovascular disease pathophysiology to address unmet needs in heart health.
About Us Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.
It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.
Led by Tassos Giannakakos, Jay Edelberg, M.D. and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.
We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.
At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.
These values are the foundation of our work, empowering us to make a real difference, every day.
Position Title: Senior Director, Internal Corporate Communications
Department: Communications
Reports To: Emily Faucette, chief communications officer
Location: South San Francisco, CA – On-site 4 days per week (Mon to Thurs)
Job Overview The Senior Director, Internal Corporate Communications will lead the strategy and execution of internal, corporate, branding, and change communications for Kardigan. This role is responsible for shaping how employees, partners, and stakeholders understand who we are, what we’re building, and how we operate - especially during moments of growth, change, and transformation.
They will be a trusted advisor to senior leadership, a strong cross-functional partner, and a hands-on executor who thrives in a fast-moving, high-expectations environment. The role is structured as a peer to the Executive Director, Product & External Communications, with distinct but complementary areas of responsibility within the communications leadership team. Together with the chief communications officer, they form the core communications leadership team, ensuring a unified, credible, and differentiated narrative across internal, corporate, product, and external audiences.
Key Responsibilities Internal Communications & Engagement
Corporate Communications
Branding & Corporate Identity
Leadership and Collaboration
Qualifications And Preferred Skills
Exact Compensation may vary based on skills, experience and location.
Pay range
$250,000 - $325,000 USD