About Us Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Giannakakos, Jay Edelberg, M.D. and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Senior Director, Internal Corporate Communications

Department: Communications

Reports To: Emily Faucette, chief communications officer

Location: South San Francisco, CA – On-site 4 days per week (Mon to Thurs)

Job Overview The Senior Director, Internal Corporate Communications will lead the strategy and execution of internal, corporate, branding, and change communications for Kardigan. This role is responsible for shaping how employees, partners, and stakeholders understand who we are, what we’re building, and how we operate - especially during moments of growth, change, and transformation.

They will be a trusted advisor to senior leadership, a strong cross-functional partner, and a hands-on executor who thrives in a fast-moving, high-expectations environment. The role is structured as a peer to the Executive Director, Product & External Communications, with distinct but complementary areas of responsibility within the communications leadership team. Together with the chief communications officer, they form the core communications leadership team, ensuring a unified, credible, and differentiated narrative across internal, corporate, product, and external audiences.

Key Responsibilities Internal Communications & Engagement

• Establish and lead Kardigan’s internal communications function to connect employees to our mission, business objectives, culture and values in a meaningful way.
• Develop and execute a cohesive strategic plan that drives alignment, clarity, and engagement across a growing, organization with multiple sites.
• Lead internal channels and content, including All Hands meetings, leadership updates, organizational announcements, change management and potential new platforms for innovative enterprise communications connectivity.
• Partner with HR, Legal and leadership to support culture-building initiatives, employee engagement, and organizational change.
• Collaborate with IT to identify the appropriate resources, platforms and tools to consistently reach and connect employees across company sites.
• Translate complex scientific, operational, and strategic topics into clear, compelling messages for diverse internal audiences.

Corporate Communications

• Support corporate narrative development and ensure consistent messaging across internal and external audiences.
• Collaborate with Investor Relations to ensure consistent pull-through of Kardigan’s corporate narrative, strategy, and milestones across diverse internal audiences.
• Draft and manage executive communications, including leadership remarks, internal memos, presentations, and company-wide updates.
• Partner closely with Legal, HR, Business Development, and leadership to ensure communications are aligned, accurate, and well-sequenced.
• Ensure communications reflect Kardigan’s values, operating principles, and long-term vision.

Branding & Corporate Identity

• Partner with the Chief Communications Officer to evolve and steward Kardigan’s corporate brand - including the integration of new companies, assets and business areas resulting from M&A - to ensure consistency across internal materials, environments, and touchpoints.
• Collaborate with cross-functional teams and external agencies on branding initiatives, corporate storytelling, and visual identity.
• Oversee development of high-quality corporate assets, including videos, presentations, signage, and internal brand materials.

Leadership and Collaboration

• Exercise excellent judgment, integrity, and transparency in making decisions that are in the best interest of the Company, our stakeholders and most importantly the patients we serve.
• Educate, influence and successfully collaborate with cross functional teams, company management, department colleagues and external partners toward a shared vision and common goal; comfort with reaching compromise and managing conflict.
• Consistently model Kardigan leadership, culture and core values.

Qualifications And Preferred Skills

Exact Compensation may vary based on skills, experience and location.

Pay range

$250,000 - $325,000 USD