
Probably Genetic helps people with unexplained symptoms get answers fast by combining an online symptom assessment with clinical-grade genetic testing. The company identifies likely rare-disease cases with ML and LLM-powered symptom checkers, conducts whole exome sequencing via at-home test kits with physician review, and delivers results alongside genetic counseling. It operates as a direct-to-consumer diagnostic service while offering a data and testing platform used by patient advocacy groups and drug developers. Probably Genetic partners with 50+ advocacy organizations, has served over 100,000 patients, and emphasizes CLIA/CAP compliance and HIPAA-aligned data privacy.

Probably Genetic helps people with unexplained symptoms get answers fast by combining an online symptom assessment with clinical-grade genetic testing. The company identifies likely rare-disease cases with ML and LLM-powered symptom checkers, conducts whole exome sequencing via at-home test kits with physician review, and delivers results alongside genetic counseling. It operates as a direct-to-consumer diagnostic service while offering a data and testing platform used by patient advocacy groups and drug developers. Probably Genetic partners with 50+ advocacy organizations, has served over 100,000 patients, and emphasizes CLIA/CAP compliance and HIPAA-aligned data privacy.
About Probably Genetic Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.
We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it.
Probably Genetic has raised multiple rounds of funding from Silicon Valley’s best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.
About The Role We’re looking for a Senior Data Engineer who’s excited to help shape the future of how we use data to make better decisions and improve patient lives. In this role, you’ll establish our data engineering architecture and build the pipelines that power both internal insights and our commercial data products. Your work will help drive clarity, impact, and growth across the company.
What you will do
Who you are
We’re excited to meet candidates from all backgrounds who are eager to learn, grow, and make an impact. Here are a few things that will help you thrive in this role:
Some things that are not required, but you could learn on the job:
As with all new hires at Probably Genetic, you will also need to be:
The salary range for this role is $150,000-$190,000 annually. Actual compensation offered will depend on several factors including but not limited to: work experience, education, skill level, and/or other business and organizational needs. This is a hybrid role that will requires working on-site 3 days a week (Tuesday, Wednesday, Thursday) in San Francisco. Local candidates only. Relocation is not currently offered for this role. What we offer at Probably Genetic:
Probably Genetic is committed to fostering a welcoming and inclusive work environment for people of all genders, sexuality, ethnicity, socioeconomic background and life experiences. We urge candidates of all backgrounds to apply. If you require specific accommodations as you interview or consider working with us, please let us know.
Compensation Range: $150K - $190K