Output Biosciences

Output Biosciences is pioneering Biologically-Aware Generative AI to understand complex biological systems, aiming to build Large Biological Models that can generate breakthrough medicines. The company is led by experienced founders in AI-driven biotech, physicians, and researchers, positioning itself at the forefront of biology and generative AI to transform disease diagnosis, treatment, and prevention. With a strong focus on advancing health, Output Biosciences is well-positioned in the biotech market, leveraging its unique generative AI architecture to handle complex biological data.

Biological ModelsBiotechDisease DiagnosisGenerative AIMedicinePreventionTreatmentoutputbio.com

Output Biosciences

Biological ModelsBiotechDisease DiagnosisGenerative AIMedicinePreventionTreatmentoutputbio.com

HQNew York City, US

Team Size4

Open Jobs4

Total Funding-

Latest Fundraise5 years ago

TL;DR

Focus: Biologically-aware generative AI for modeling complex biological systems and enabling medicine generation

Product: Building "Large Biological Models" and a generative AI architecture for extremely long, nonlinear, fragmented, high-dimensional biological data

Stage & Investor: Pre-Seed; backed by Y Combinator

Headquarters: New York, NY

Founded: 2021

Company Overview

Problem Domain

AI-driven biotechnology / drug discovery and therapeutics

Founded

2021

Industry

Biotechnology Research

Tech Stack

Amazon (Virginia Region)

Common Crawl

CommonCrawl Top 50m

Funding Track Record

Pre-Seed- 2021-08-22

Investor Signal

“Backed by Y Combinator”

Founders

What we do

TL;DR

Company Overview

Funding Track Record

Founders

What we do

Output Biosciences

Biological ModelsBiotechDisease DiagnosisGenerative AIMedicinePreventionTreatmentoutputbio.com

Output Biosciences

Biological ModelsBiotechDisease DiagnosisGenerative AIMedicinePreventionTreatmentoutputbio.com

HQNew York City, US

Team Size4

Open Jobs4

Total Funding-

Latest Fundraise5 years ago

TL;DR

Focus: Biologically-aware generative AI for modeling complex biological systems and enabling medicine generation

Product: Building "Large Biological Models" and a generative AI architecture for extremely long, nonlinear, fragmented, high-dimensional biological data

Stage & Investor: Pre-Seed; backed by Y Combinator

Headquarters: New York, NY

Founded: 2021

Related Companies

Company	HQ	Industry	Total Funding
Asimov	🇺🇸Boston, US	BiotechnologyDeepTech	$205M
Serinus Biosciences	🇺🇸New York City, US	BiotechnologyDeepTech	$650K
Formation Bio	🇺🇸New York City, US	BiotechnologyDeepTech	$528M
Bioptimus	🇫🇷Paris, FR	BiotechnologyData and AnalyticsDeepTechSoftware	$76M
Synthesize Bio	🇺🇸Seattle, US	BiotechnologyDeepTech	$10M

Company Overview

Problem Domain

AI-driven biotechnology / drug discovery and therapeutics

Founded

2021

Industry

Biotechnology Research

Tech Stack

Amazon (Virginia Region)

Common Crawl

CommonCrawl Top 50m

Funding Track Record

Pre-Seed- 2021-08-22

Investor Signal

“Backed by Y Combinator”

Founders

What we do

Related Companies

Company	HQ	Industry	Total Funding
Asimov	🇺🇸Boston, US	BiotechnologyDeepTech	$205M
Serinus Biosciences	🇺🇸New York City, US	BiotechnologyDeepTech	$650K
Formation Bio	🇺🇸New York City, US	BiotechnologyDeepTech	$528M
Bioptimus	🇫🇷Paris, FR	BiotechnologyData and AnalyticsDeepTechSoftware	$76M
Synthesize Bio	🇺🇸Seattle, US	BiotechnologyDeepTech	$10M

Join the Team

Senior Computational Biologist (NYC)

RemoteNew York, NY, US

Remote • New York, NY, US

The Role Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales - from molecules to organisms - enabling us to predict, understand, and program living systems in ways never before possible.

Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator.

As a Senior Computational Biologist, you'll work alongside members of our research team and our founders to develop AI systems capable of complex biological reasoning across multiple scales.

Teeming tracks opportunities at over 24,000 AI startups, then works with you to find (and land) the one you'll love.

Mobile Developer

Part-timeCambridge, GB

Part-time • Cambridge, GB

Backend Developer

ContractNovi Sad, RS

Contract • Novi Sad, RS

Software Engineer

Full-timeTel Aviv

Full-time • Tel Aviv

AI Researcher

Full-timeAmsterdam, NL

Full-time • Amsterdam, NL

Product Designer

Part-timeAustin, US

Part-time • Austin, US

Frontend Developer

Part-timeAmsterdam, NL

Part-time • Amsterdam, NL

You will develop machine learning methods to extend our predictive and generative platform

You will design and execute computational pipelines to validate and prioritized de novo generated molecules using state of the art tools

You will use your deep understanding of biology to design novel therapeutics for hard-to-target proteins with our generative models

You will analyze and integrate large-scale biological datasets

Your work will directly impact the development of our biologically-aware AI platform, transforming the landscape of medicine

Make a real tangible impact on millions of lives by pushing the boundaries of AI in biology.

Who We're Looking For

You have a PhD in a biological field and strong programming skills in Python
You have experience with computational biology tools such as structure prediction, molecular docking and virtual screening
You have experience working with Protein or Chemical Language Models
You like to work collaboratively in a fast-paced startup environment
You are passionate about using data science to unlock the secrets of biology
You exhibit a proactive approach to problem-solving, thinking beyond the specific task, taking ownership of challenges, and pride in solving them
You have a mature mindset in ambiguous situations, helping to frame questions and seek clarity while making decisions in the face of uncertainty
You have excellent communication skills and can clearly articulate complex technical concepts

You have hands-on experience building AI/ML using PyTorch and Lightning
You have experience with cloud computing platforms like AWS
You have hands-on biology laboratory experience
You have contributed to peer-reviewed publications in computational biology
You have knowledge of machine learning techniques applied to biological data

❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions.

🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards.

🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community.

📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner.

🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling.

We encourage new and different ideas, creativity and contrarian thinking
Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you
You own your day-to-day management. What we care about is that we all hit our milestones
Competitive salary and equity in a growing, well-funded startup
Excellent medical, dental, and vision coverage

Compensation Range: $150K - $250K