
Noetik is an AI-native biotechnology company focused on revolutionizing cancer immunotherapy discovery and development. By combining self-supervised learning with the industrial-scale generation of…

Noetik is an AI-native biotechnology company focused on revolutionizing cancer immunotherapy discovery and development. By combining self-supervised learning with the industrial-scale generation of…
Location: South San Francisco, CA
Stage / Funding: $55M total disclosed
Focus: AI-native biotechnology for precision cancer immunotherapy using multimodal spatial-omics
Founders / Leadership: Ron W. Alfa (Co-founder, CEO) and Jacob Rinaldi (Co-founder)
Cancer immunotherapy discovery and development; modeling tumor microenvironment complexity for precision oncology.
2022
Biotechnology
$14,000,000
Seed round of $14.0M reported in Dealroom (Sep 2023).
Subsequent round entry dated August 2024 reported by Dealroom/Crunchbase.
Most recent funding date listed as 2024-09-12 in company snapshot.
“Includes strategic and institutional investors such as Amazon Web Services, Khosla Ventures, Polaris Partners, Zetta Venture Partners, DCVC, and others.”
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WHY THIS MATTERS
NOETIK is a frontier therapeutics company harnessing AI to deeply understand human biology and redefine clinical outcomes in oncology. Leveraging the largest proprietary multimodal oncology dataset of its kind, uniquely integrating spatial biology, NOETIK’s foundation AI models precisely match therapeutic targets to patient subpopulations and accurately predict clinical efficacy. This AI-first approach elevates therapeutic development from probabilistic guesswork to precision science.
THE OPPORTUNITY
We are seeking a highly driven Senior Biosample Operations Manager to lead strategic biosample sourcing during an exciting period of exponential growth at Noetik. As we scale, we are rapidly developing our biorepository to be pan-cancer and then to expand beyond oncology. The person in this role will lead the design and build-out of our biorepository during this period of scaling and beyond, enabling massive multi-modal data generation in our laboratory. To do this, they will work collaboratively with multiple teams at Noetik, including Machine Learning, Engineering, Therapeutics, and Data Generation. In the future, this person is anticipated to help design and implement sample strategies in Noetik internal and/or partnered clinical trials. This role is a high-ownership, high-visibility role on our Platform team, reporting to the Senior Director of Biomarker and Scientific Operations.
ROLE AND RESPONSIBILITIES
This is a mission-critical role where you will drive the future of biosample sourcing strategy and biorepository innovation to power large-scale data generation. You will be responsible for vendor outreach and management, executing multiple projects simultaneously, and scaling quickly to enable ever growing data generation requirements. Success in this role will require deep expertise in biosample operations and histology workflows, paired with the ability to anticipate challenges, solve problems proactively, and execute with precision. This role is a balance of big picture strategy with hands-on building, requiring a strong scientific background and confidence to independently execute projects while maintaining precise organization and attention to detail. If you thrive in a fast-paced, dynamic environment, this is an opportunity to make a meaningful impact at scale.
Responsibilities include:
REQUIRED EDUCATION & EXPERIENCE
QUALIFICATIONS AND SKILLS
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