
Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class…

Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class…
Founded: 2023 (spin‑out from Gustave Roussy)
Headquarters: Villejuif / Paris region, France
Focus: AI-powered precision oncology using patient-derived tumor avatars (organoids) and multimodal data
Products: O-Predict and O-Validate (AI commercial products)
Known funding: ≈ €14–15M across 2023–2024 (seed / pre-seed rounds)
Preclinical and clinical de-risking for oncology drug discovery and development, with initial tumor-type focus on colorectal and pancreatic cancers.
2023
Biotechnology Research
€3,000,000
Reported pre-seed/seed round
€11,000,000
Seed round with participation from multiple investors
“Singular; Bpifrance; Speedinvest; Verve Ventures; HCVC; SistaFund; Amazon Web Services”
Orakl Oncology is pioneering a new paradigm in cancer drug development by building the world’s largest cohort of patient-derived organoid (PDO) avatars. Through our unique platform, we generate extensive multi-modal data from these avatars to discover and validate new oncology therapeutics with real-world patient relevance.
We are seeking a Senior AI Engineer to own the technical vision and execution of our AI strategy. This is a uniquely high-impact role at the intersection of AI engineering and the scientific processes developed internally: you will design, build, and operate the production-grade agentic systems that power our predictive oncology platform, and by the same token support the scientists and clinicians working to improve patients’ lives. You will be embedded at the heart of a fast-paced, multidisciplinary team of experimental biologists, data scientists, and engineers.
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Lead Agentic Strategy & Architecture
Own the technical vision and architecture for agentic systems at Orakl: multi-step workflows integrating tools, memory and state management, planning, and human-in-the-loop controls.
Stay at the forefront of the field — continuously monitor state-of-the-art agentic methods, evaluate their applicability to Orakl’s context, and drive adoption of relevant innovations across the team.
Design, ship, and operate production-grade agentic systems that answer key health challenges for cancer patients, including:
Engineering
A builder at heart — you thrive when you’re shipping working systems, not writing perfect specifications.
Deeply curious about the potential of LLMs and agentic AI, and excited to apply these technologies in a domain where they can genuinely improve health outcomes.
A collaborative technical leader who enjoys raising the bar across teams through mentorship, clear technical communication, and well-reasoned architectural choices.
Comfortable navigating ambiguity and operating at the frontier of a fast-evolving field, where the right answers often don’t exist yet.
Energized by working in a multidisciplinary environment alongside experimental scientists, clinicians, and product engineers.### Minimum Qualifications
Master’s degree in a quantitative field (Computer Science, Mathematics, Engineering) and 3+ years of experience building production software, including meaningful hands-on experience deploying LLM-powered applications.
Strong proficiency in Python and modern AI/ML tooling; familiarity with agentic frameworks (e.g., LangChain, LlamaIndex, Strands, or equivalent).
Proven track record of taking AI systems from prototype to production, including testing, monitoring, and iteration in a real-world environment.
Solid software engineering fundamentals: API design, data pipelines, version control, cloud infrastructure.
Ability to influence technical direction through collaboration and constructive challenge, not just authority.