What will you be doing?

• Design, develop, and apply cheminformatics and AI workflows to support small molecule discovery, including compound prioritization, library design, and structure-activity relationship analysis

• Develop and deploy machine learning models using proprietary chemoproteomics, chemistry, and experimental datasets to drive biological insight and project decision-making.

• Partner closely with medicinal chemistry and drug discovery teams as an embedded analytics and AI expert, act as a liaison to the computational and medicinal chemistry departments and project teams.

• Design novel algorithms and analytical approaches tailored to Frontier's unique datasets and scientific questions.

• Stay current with emerging advances in AI, cheminformatics, and computational drug discovery, and lead internal adoption of promising methods.

• Communicate results, hypotheses, and recommendations clearly through presentations, documentation, and scientific discussions.

• Contribute to scalable, maintainable, and reproducible software and analytics solutions following best practices.

Requirements

Traits we believe make a strong candidate:

• PhD in computational or quantitative discipline such as cheminformatics, computational chemistry, computer science, data science, computational biology, chemical engineering, or a related field.

• Strong programming skills in Python

• Experience applying AI to medicinal chemistry or cheminformatics problems (e.g., molecular representations, fingerprints, generative models, transformers, pretraining strategies, property prediction, virtual screening, ADMET modeling)

• Comfort with modern software development practices including version control, testing, containerization, and cloud-based computing environments (AWS experience is a plus).

• Ability to work independently while thriving in a highly collaborative, cross-functional environment.

• Excellent written and verbal communication skills.

• Legally authorized to work in the United States.

Leveling Guidelines

• Scientist

• Minimum 1+ years of relevant industry experience.

• Demonstrated ability to independently or with limited guidance design and execute computational and AI approaches for drug discovery problems.

• Proven track record of leading complex analytical strategies and influencing discovery programs through data-driven insights.

• Ability to effectively collaborate with experts from other domains

Benefits

• Health Care Plan (Medical, Dental & Vision)
• Retirement Plan (401k, IRA)
• Life Insurance (Basic, Voluntary & AD&D)
• Paid Time Off (Vacation, Sick & Public Holidays)
• Family Leave (Maternity, Paternity)
• Short Term & Long Term Disability
• Training & Development
• Free Food & Snacks
• Wellness Resources
• Stock Option Plan

At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $130,000 - $175,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.

This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.