At Two Bear Capital we believe in partnering with our founders to build the best companies possible. We look forward to working with you for FYR Bio' s new Business Development Lead.

Business Development Lead / Senior Manager, Biopharma Partnerships (Neuro)

Remote | Contract / Fractional (Preferred) or Full-Time

Overview

We are seeking a senior, commercially driven Business Development professional to originate, structure, and help close strategic partnerships with biopharma companies, with a focus on neuro-oncology and neurodegenerative disease.

This is a high-impact “hunter” role focused on building relationships with key decision-makers and driving large, multi-phase engagements . While early engagements may begin with smaller studies, the core objective is to establish long-term, high-value partnerships.

We are open to structuring this role as fractional/contract or full-time , with a preference for a contractor model to start.

Role Focus

• Build and convert a pipeline of strategic biopharma opportunities
• Engage senior stakeholders across: Business Development, Clinical Development, Medical Affairs, Strategy and Innovation
• Drive high-value deal creation, not high-volume outreach
• Help shape how engagements are structured, priced, and expanded over time

Required Experience

• 7–15+ years in business development, partnerships, or commercial roles within: Biopharma, CROs, life sciences services, or consulting
• Proven track record of: Closing or materially contributing to large, complex B2B deals, selling into pharma/biotech organizations and navigating multi-stakeholder environments
• Strong understanding of drug development and stakeholder landscape

Preferred Profile

• Existing network within neuro-oncology, CNS, or related therapeutic areas
• Experience structuring multi-phase or strategic partnerships
• Strong negotiation and deal-making capabilities
• Entrepreneurial mindset; comfortable operating in an early-stage environment
• Ability to operate independently while collaborating closely with leadership

Key Responsibilities:

Strategic Pipeline Developmen t

• Identify and prioritize target pharma/biotech accounts within neuro/CNS
• Leverage existing network and targeted outreach to access decision-makers
• Relationship development: build trust with senior stakeholders across target organizations and establish credibility within the neuro-focused biopharma ecosystem

Deal Origination & Structuring

• Lead early-stage conversations and opportunity shaping
• Collaborate with internal leadership to define scope, pricing, and long-term
• partnership opportunities

Deal Progression & Closing Support

• Drive opportunities from initial engagement through proposal and negotiation
• Navigate complex stakeholder and procurement environments

Commercial Strategy Input

• Provide feedback on positioning, messaging, and market dynamics
• Help refine go-to-market approach based on real-world interactions

What Success Looks Like

• Development of a high-quality pipeline within target neuro-focused accounts
• Access to senior decision-makers across pharma/biotech organizations
• Progression and closure of large ($250K–$1M+) strategic engagements
• Establishment of long-term partnerships and expansion opportunities

Preferred Profile

• Existing network within neuro-oncology, CNS, or related therapeutic areas
• Experience structuring multi-phase or strategic partnerships
• Strong negotiation and deal-making capabilities
• Entrepreneurial mindset; comfortable operating in an early-stage environment
• Ability to operate independently while collaborating closely with leadership

Why Join

• Opportunity to directly influence company trajectory through high-value partnerships
• High ownership and visibility with leadership
• Flexibility in engagement structure (contract or full-time)
• Ability to shape the commercial strategy in a growing organization
• Work at the intersection of innovation and neuroscience