
The AI Neuroscience company. We're hiring AI Bio Researcher & ML Researcher Engineers in SF - https://www.primamente.com/join-us/

The AI Neuroscience company. We're hiring AI Bio Researcher & ML Researcher Engineers in SF - https://www.primamente.com/join-us/
About Prima Mente Prima Mente’s goal is to deeply understand the brain, to protect the brain from neurological disease and enhance the brain in health. We do this by generating our own data, building brain foundation models, and translating discovery to real clinical and research impact.
Role focus - Foundation Models for Biology You will play a pivotal role in designing, implementing, and scaling foundational AI models and infrastructure for multi-omics at massive scale. Your work will directly drive breakthroughs in scientific understanding and contribute to transformative applications in medicine and biology.
Key Tasks:
Expected Growth In 1 month you will be responsible for running initial experiments with state-of-the-art machine learning models, reviewing and implementing cutting-edge research papers, and optimizing existing code for efficiency and accuracy.
In 3 months you will directly own and have created a prototype model architecture, demonstrated significant algorithmic improvements, and contributed to scaling methods for large-scale data ingestion and training.
In 6 months , you’ll have developed a high-performance version of a foundation model, implemented key algorithmic optimizations that boost scalability and throughput, and published internal benchmarks demonstrating significant research impact.
Why Join Us:
Who You Are You want to redefine what’s possible at the frontier of AI and biology.
Ideal experience
Deep understanding of state-of-the-art machine learning methodologies and proven experience in translating them into practical solutions.
Solid foundation in distributed computing principles, parallel processing, and algorithmic efficiency.
Experience optimizing ML algorithms for performance, memory efficiency, and compute resource utilization.
Skilled in designing and implementing scalable data pipelines capable of rapid ingestion, transformation, and processing.
Deep expertise in modern ML frameworks and tools (e.g., PyTorch, JAX, TensorFlow), and familiarity with state-of-the-art training and inference workflows.
Skilled in clearly articulating complex ideas, effectively communicating why particular approaches succeed or fail, and providing insightful critical analyses.
Experience of building highly collaborative research teams.
Track record of working on hard problems for long periods of time.
High agency with the ability to jump on any task as needed.
Demonstrated experience training, optimizing, and deploying large-scale models (7B+ parameters).
Low level algorithm optimisation
quantization (8bit or lower)
JIT compilation
XLA/Mosaic/Triton/CUDA
Hardware optimisation (GPU/TPU/HPU)
Finetuning Optimization (QLora, QDora)
Large scale data above 2T tokens
Location Based in San Francisco, US or London, UK. We support visa applications.
Culture Insight
What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands-on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous.
Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence.
We arrange our lives so we can work in person as much as possible.
Our Values Exceptional performance at exceptional pace
Inquisitive discovery
Radical candour
Purposeful individuality
Patient impact at scale