
Helical is focused on providing open-source bio foundation models, particularly in the realm of single-cell analysis, enabling scientists to leverage advanced AI tools for their research. Their platform offers a community-driven approach, allowing users to fine-tune and integrate these models into their workflows, thereby enhancing research capabilities in the biological sciences. With a commitment to accessibility and collaboration, Helical positions itself as a key player in the AI for bio sector, catering to researchers and developers looking for innovative solutions.

Helical is focused on providing open-source bio foundation models, particularly in the realm of single-cell analysis, enabling scientists to leverage advanced AI tools for their research. Their platform offers a community-driven approach, allowing users to fine-tune and integrate these models into their workflows, thereby enhancing research capabilities in the biological sciences. With a commitment to accessibility and collaboration, Helical positions itself as a key player in the AI for bio sector, catering to researchers and developers looking for innovative solutions.
What they do: Platform for Bio Foundation Models enabling in-silico experiments for drug discovery and R&D
HQ: Luxembourg
Stage / funding: Seed (closed Jun 28, 2024)
Founders: Mathieu Klop; Maxime Allard; Rick Schneider
Drug discovery and pharmaceutical R&D using AI-driven in-silico experiments
2024
Biotechnology Research
Reported seed round with seven investors
“Has participation from early-stage investors and angel/backer set including Frst and named investors”
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About Us
Helical is pioneering the use of Bio Foundation Models to make biology computable and reshape how medicines are discovered. Our platform empowers pharma teams to apply these models in workflows such as target identification, biomarker discovery, patient stratification, perturbation prediction and more.
Helical raised over 3M€ in its Seed-funding round from leading VCs in France and the US as well as prominent Business Angels s.a. the CEO of HuggingFace, the CEO & CTO of Cohere, …
Join us to be part of the early-stage fast-growing founding team of Helical driving groundbreaking innovation and play a decisive role in contributing towards our ambitious goals, while being a part of an inspiring, collaborative and entrepreneurial culture in the heart of Europe.
Our github: https://github.com/helicalAI/helical/
Our Website: https://www.helical-ai.com/
Your Role
As a Machine Learning Engineer - Scaling at Helical, you’ll build, optimize, and scale real-world applications of bio foundation models
You’ll work closely with researchers and product engineers to productionize model training, inference, and deployment workflows. You’ll also help push the limits of foundation models by prototyping new methods, contributing to our core ML infrastructure, and translating research into fast, iterative code.
This is a deeply technical role with high ownership — ideal for engineers who want to operate at the bleeding edge of AI infrastructure, model development, and system design.
What You’ll Do
Requirements
Essentials
Bonus Points
Our Perks
🧬 Every employee is a co-owner of Helical — you’ll join as part of the founding team. 🚀Operate at the cutting edge of AI — from foundational research to real deployment.
🤖Access to world-class compute infrastructure (via our supercomputing partner luxProvide, part of NVIDIA Inception).
💻Collaborate with a global network of top-tier AI researchers and engineers.
Locations
Helical is headquartered in Luxembourg and London.
This role requires alignment with one of our two core locations. We’re flexible on hybrid vs. in-office setup