
Delfi Diagnostics detects cancer early, when it is most curable, using high-precision non-invasive blood tests. It uses artificial intelligence and genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients. The company was founded in 2019 and is based in Baltimore, Maryland.

Delfi Diagnostics detects cancer early, when it is most curable, using high-precision non-invasive blood tests. It uses artificial intelligence and genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients. The company was founded in 2019 and is based in Baltimore, Maryland.
Mission: Early cancer detection via fragmentomics-based, ML analysis of cell-free DNA from blood
Founded: 2019
Lead product / tech: DELFI-TF (genome-wide cfDNA fragmentation analysis with machine learning)
Notable financing: $225M Series B (July 18, 2022); total funding reported ~$330.5M
Headcount (approx.): 176 employees
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Early cancer detection and treatment monitoring using liquid biopsy (fragmentomics of cell-free DNA).
2019
Biotechnology Research
$225,000,000
Announced Series B to develop portfolio of liquid biopsy tests
“Participation from strategic and institutional investors including Eli Lilly, Point72, Brown Advisory, Menlo Ventures, OrbiMed, Samsara BioCapital, T. Rowe Price, and others”
About Us
Our mission is to cure cancer through high performance, accessible early cancer detection. That means saving lives.
Delfi Diagnostics is a Johns Hopkins spinoff focused on the non-invasive detection of cancer at earlier stages, when it is most curable. DELFI uses artificial intelligence and whole genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients with cancer. These analyses are performed through simultaneous examination of millions of DNA sequences using machine learning to identify tumor-specific abnormalities.
In our passionate pursuit to radically improve health outcomes, we serve humanity when we:
Lead with Science, Anchor in Pragmatism : We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction.
Build With & For All : We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class
Put We over I : We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us--win. We show up with empathy, humility, and integrity at every step of the journey.
About the Role
In this role, you will be responsible for the leadership and support of the daily laboratory operations, to and including the management of the staff. The Laboratory Operations Manager also performs high complexity laboratory testing directly for cancer detection via next generation sequencing. The Laboratory Operation Manager will be the first point of contact for troubleshooting technical issues. You will be responsible for maintaining operations and meeting project deliverables for laboratory programs such as the Equipment Management and Reagent Management programs. You will be working in a cross-functional capacity between the Clinical Laboratory, Client Services, Quality and Regulatory, the Laboratory Director, and other teams (e.g., Assay Development and Software Engineering). Given the wide variety of tasks involved in this position, the Laboratory Operation Manager must demonstrate the ability to analyze complex issues and make sound decisions in a timely manner, commit to providing the highest quality test results, work cross-functionally, and adapt quickly to evolving circumstances.
What You'll Do
What You'll Have Accomplished 12 Months From Now
What You'll Bring to DELFI
Required
Preferred
An equal opportunity employer
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
Must possess an active and valid Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license issued by the state of California pursuant to Division 2, Chapter 3 of the California Business and Professions Code or to practice medicine, osteopathy, or podiatry pursuant to Division 2,
Chapter 5 of the California Business and Professions Code appropriate to the specialty being performed
Must fulfill requirements stated in Title 17 California Code of Regulations Section 1036.1
Must fulfill requirements stated in 42 CFR 493.1461 or 493.1462
Must fulfill requirements stated in the College of American Pathologists Molecular Pathology Checklists
Previous leadership/management experience
BS in Biomedical Laboratory Sciences, Clinical Science, or equivalent