
Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class…

Orakl Oncology is a pioneering precision oncology company founded in 2023 as a spin-off from the Gustave Roussy Institute, focused on accelerating oncology drug development through a first-in-class…
Founded: 2023
Headquarters: Villejuif, Île-de-France, France
Focus: AI-powered precision oncology platform for drug development
Flagship products: O-Predict; O-Validate
Notable funding: Seed round (Dec 2024); ~€11M–€15M total raised
28 employees
Cancer drug development, with an emphasis on colorectal and pancreatic cancers
2023
Biotechnology Research
≈€11,000,000
Seed round announced Dec 3, 2024; reporting cites nondilutive support from Bpifrance and total capital raised to date near €15M in some sources.
“Bpifrance; Singular; additional investors recorded (Amazon Web Services, HCVC, SistaFund, Speedinvest, Verve Ventures)”
Position Overview
Orakl Oncology develops large cohorts of patient-derived organoids (PDO), from which we generate large volumes of data and train proprietary AI algorithms to help pharma teams develop new treatments for patients. In practice: we culture ~100 PDOs in parallel at any given time in the lab, screen dozens of drugs weekly and own a growing biobank with and an expanding client portfolio.
As Lab Manager, you will be responsible for the organisation, structuring and overall smooth operation of Orakl Oncology’s labs. You will ensure the consistency of infrastructures, processes and operational standards to guarantee the laboratory’s scientific, technical and regulatory performance. We expect the lab manager to improve and optimise the Orakl laboratory workflows and standards.
You will have a direct and strong impact on the scientific and operational quality of the data we produce. We expect you to work with a high level of autonomy and you will report directly to the Laboratory Director.
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If you are looking for a role where building matters as much as maintaining, this is it.
Your Responsibilities
Propose and lead end-to-end structuring and optimisation projects for the laboratory, in alignment with the Laboratory Director;
Identify strategic equipment needs and conduct active technological and methodological monitoring;Need-to-have/Profile
Master’s degree (or equivalent) in life sciences (biology, biochemistry, biotechnology or related field);
Significant experience (3+ years) in a laboratory environment, including hands-on operational management or coordination;
Proven experience in equipment maintenance management and laboratory infrastructure oversight;
Strong knowledge of laboratory quality systems (SOP writing, document management, traceability);
Familiarity with regulatory and biosafety requirements applicable to laboratories handling human biological samples;
Demonstrated ability to structure processes and organise workflows;
Experience in inventory management and consumables procurement;
Self-driven, rigorous and able to prioritise in a multi-project environment;
Excellent communication and cross-team coordination skills;
Fluent in English, knowledge of French is a plus
Nice-to-have
HR Call (25 minutes call) – An initial discussion to better understand your background, experiences, and motivations.
Technical Interview (60 minutes call) – A deep dive into your technical skills and expertise relevant to the role.
Technical Case (30 minutes presentation + discussion) - A case study or problem-solving exercise to assess your strategic thinking and analytical abilities. If possible this can be done in person.
Founder Interview: As final step of our recruitment process, you will meet the founders of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values.