R&D project manager assistant - Internship

Unlock the Future of Drug Discovery.

Join 4Dcell and become part of a pioneering French biotech on a mission to transform drug discovery and toxicology. We’re engineers and biologists united by a single goal: to replace animal testing with intelligent, in vitro “organ-in-a-well” models that deliver unprecedented predictive power to drive tomorrow’s therapies.

4Dcell has developed two flagship solutions: the SmartHeart™ Platform, which recreates human ventricular tissue in a standard 96-well plate, and the first-in-class SmartSphero™ Technology, enabling the generation of a wide range of organoids.

You’ll collaborate with leading biophysicists, engineers, and biologists to tackle the toughest health challenges, from heart failure and immuno-oncology to pancreas and renal diseases. We combine ambition with a supportive, curiosity-driven culture.

Why intern with us?

• Freedom and responsibility to structure and lead your own projects

• Hands-on exposure to game-changing technologies

• Apply marketing skills on a new, growing, exciting and revolutionary market

• A team that values collaboration, growth, and fun

• Membership in a high-energy, fast-growing team developing truly game-changing, high-tech products

• The opportunity to navigate both a commercial start-up environment and an R&D scientific setting

• Close collaboration with experts in technology, marketing, sales, application science and operations

• Step into a role where your work accelerates drug discovery, improves patient outcomes, and builds amore ethical pharmaceutical future.

Context

Within our R&D team, you will work hands-on with experimental protocols to characterize cardiac pathologies and cardiac cell line maturation.

Main Responsibilities

Executing Design of Experiments (DoE)

• Prepare culture media and reagent dilutions

• Seed cells at defined densities according to the DoE matrix

• Record all steps and observations in the lab notebook (LIMS/Excel)Data

Processing & Analysis

• Import raw metrics (viability, marker expression, contractility)

• Create summary tables and plots to compare conditions

• Draft concise experimental summaries with actionable conclusions

3D Cell Culture

• Set up cardiac organoid (SmartHeart)

• Conduct immunofluorescent staining and confocal imaging

• qPCR analysis

Deliverables

• Complete experimental records (DoE details, raw results, observations)

• Analyzed datasets with clear graphical outputs

• Updated operational protocols

• Brief reports for each experimental campaign

Environment & Tools

• Equipment: CO₂ incubators, laminar-flow hoods, confocal microscope

• Software: LIMS/Excel, GraphPad Prism, R or basic Python notebooks

• Techniques: DoE, 2D & 3D cell culture, immunofluorescence

Candidate Profile

• Master’s student in Biology, Biotechnology or Biomedical Engineering

• Hands-on experience with cell culture (2D and/or 3D)

• Comfortable with data entry and analysis

• Experienced in Molecular Biology

• Organized, experimentally rigorous and proactive

• Good technical English

Duration & Terms

• 6-month internship, starting January or February 2026

• Based in Montreuil (Paris), France

Legal internship stipend 650€ + partial transport reimbursement