
Manifold Bio is a biotechnology company leveraging its m Design platform to revolutionize drug discovery through in vivo biologics design. The company combines a unique 100-plex pooled in vivo screening technology with AI-guided protein design to create tissue-targeted medicines, particularly for neurological disorders. Their innovative approach allows for the simultaneous evaluation of multiple protein designs, enhancing therapeutic delivery and addressing significant unmet medical needs. With a focus on brain shuttling and engineered protein delivery vehicles, Manifold is positioned to lead in the development of potent and tolerable medicines, establishing a strong pipeline and partnership opportunities in the biopharmaceutical landscape.

Manifold Bio is a biotechnology company leveraging its m Design platform to revolutionize drug discovery through in vivo biologics design. The company combines a unique 100-plex pooled in vivo screening technology with AI-guided protein design to create tissue-targeted medicines, particularly for neurological disorders. Their innovative approach allows for the simultaneous evaluation of multiple protein designs, enhancing therapeutic delivery and addressing significant unmet medical needs. With a focus on brain shuttling and engineered protein delivery vehicles, Manifold is positioned to lead in the development of potent and tolerable medicines, establishing a strong pipeline and partnership opportunities in the biopharmaceutical landscape.
Manifold Bio is a dynamic biotech company building a pipeline of targeted biologics using a novel in vivo-centric discovery approach. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.
Come join Manifold as our first full-time People & Talent professional, reporting to the COO. Fueled by a new research collaboration with Roche, we are in the midst of a rapid growth spurt from 35 to 60+ employees, and will be looking to you to help us scale gracefully and efficiently while maintaining all that we love in our onsite culture. You ideally have startup experience in discovery stage biotech, though experience scaling a successful tech company would also be relevant. The ability to flex between talent acquisition, development, employee relations, and compensation planning, and are curious about ways to use technology like Greenhouse, Google Workspace, and AI applications to make life easier. You balance empathetic people leadership with sharp business judgment and creative problem-solving.
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We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.