About Sonia One in five adults struggles with their mental health each year and many will never see a therapist. Costs are high, waitlists are long, and stigma is still a real barrier for people to not seek help. Suicide is one of the leading causes of death for young people. Therapy works, but it doesn't scale.

We're building safe AI for mental health support that's clinically as effective as the best human therapists — accessible to everyone, at a fraction of the cost, and available anytime. We've recently had a major breakthrough. In our clinical research, we're now seeing significant improvements in anxiety and depression symptoms after just 2 weeks of use. And we receive daily messages about how Sonia is changing lives.

We're a 6-person team in San Francisco, backed by Y Combinator, Moonfire, and founders of Verkada, Reddit, and Instacart.

The Role

Sonia is an AI-native product — and our clinical research is what makes it trustworthy. We've already run clinical trials showing significant symptom reduction in anxiety and depression, and we're just getting started. We need someone to own and lead our entire research program: designing and running clinical trials, driving our FDA regulatory strategy, conducting safety research, publishing in peer-reviewed journals, and building the evidence base that establishes Sonia as a clinically validated treatment. You'll also co-write grant applications with our academic collaborators to secure research funding from federal and foundation sources.

This is a high-ownership role. You'll set the research vision for Sonia by shaping what we study, how we study it, and how we communicate our findings to regulators, clinicians, and the public. You'll work directly with the founders — who are deeply involved in AI research — and collaborate with leading academic research partners in the US and Europe.

Problems you'll work on

What the work looks like

• Design study protocols, manage IRB submissions, and oversee data collection and analysis
• Collaborate closely with the engineering and product team to instrument the product for research data capture
• Translate research findings into regulatory submissions and clinical marketing materials
• Stay current on the digital therapeutics and AI therapy regulatory landscape, including FDA guidance documents and relevant precedents
• Work with external advisors and KOLs to strengthen our research credibility
• Use AI tools to accelerate your research workflows — we're an AI-native team and expect everyone to leverage these tools

Culture

We're kind to each other, we work hard, and we are thoughtful about what we're building. We're deeply mission-driven — we believe everyone deserves access to effective mental health support, and that belief shapes everything we do.

We're an AI-native team that believes a small, focused group can achieve what previously required 100 people. Everyone here has high ownership and real impact on the direction of the company. At the same time, we take clinical evidence and safety extremely seriously — moving fast never means cutting corners on rigor.

Our core team works 6 days a week together in our office in downtown SF. This role can be remote or hybrid, but we value regular in-person collaboration and prefer in person work.

Who We're Looking For

• PhD or equivalent (e.g., MD) in clinical psychology, behavioral health, or a closely related field
• Experience designing and running clinical trials (ideally efficacy RCTs) in mental health or digital health
• Track record of peer-reviewed publications in clinical psychology, behavioral health, or a related field
• Comfortable working in a fast-moving startup environment with high ambiguity, agency and ownership
• Experience working in technology or digital health environments

A few user stories from the past weeks

• A woman from the south who lives in a rural area with no therapist in proximity from her Blue Shield insurance. She has been unemployed for the past 15 years and told us that due to her chats with Sonia she gained the courage to apply for jobs again. A few days later, just before her user interview with us, she got accepted to her job and is now employed again.
• A person from Alabama who had such strong OCD and anxiety that they always needed to turn around with the car 3-4 times to check whether they actually turned off the stove. Sonia helped them get it down to one.
• The parent of 2 incarcerated sons, has built out a mantra with Sonia and is now able to go through her days with more acceptance and peace. Something that according to her, her weekly Monday morning therapist that she has been seeing for a long time hasn't managed to achieve.