This role is unlike traditional business development, focused on pipeline generation and closing new partnerships, and is unlike traditional account management, focused on expansion across multiple accounts and delivery success at a high level. Instead, this position embeds deeply in the client organization, operating comfortably at all levels from leadership to working teams, to deliver cross-functional coordination, executive-level engagement, long-range planning, and best-in-class execution across multiple parallel workstreams. The Enterprise Client Principal will serve as Beacon’s primary owner for its most important strategic accounts, and will play the central role in ensuring partnerships deliver on their scientific, clinical, and commercial objectives.

This role is a senior individual contributor role in the Life Sciences organization, reporting directly to the Chief Business Officer, with close collaboration across Science, Clinical Operations, Program Management, Business Development, Finance, Legal, and other Executive Leadership. With success, there is potential to build a team with a similar mandate, expanded across a larger number of accounts.

This position is based in Boston.

What Success Looks Like

• Serve as the primary relationship manager and commercial lead for one or more enterprise strategic partnerships, acting as the single-threaded owner for partnership success.
• Build and maintain trusted, executive-level relationships with partner stakeholders across scientific, clinical, operational, and commercial functions.
• Ensure alignment between Beacon and partner objectives, timelines, and expectations throughout the lifecycle of the partnership.
• Lead post-contract partnership planning, including governance structures, operating cadences, success metrics, and communication frameworks.
• Partner closely with Program Management and cross-functional teams to ensure seamless execution of contracted work and proactive issue resolution.
• Identify opportunities to expand scope, deepen engagement, and grow partnership value over time through new use cases, programs, or services.
• Translate Beacon’s scientific and technical capabilities into clear, strategic value for partners’ clinical development programs in neurology, psychiatry, and sleep-related disorders.
• Act as a thought partner to customers by providing scientifically grounded insights that inform study design, data strategy, and clinical decision-making.
• Prepare and deliver high-impact presentations and strategic readouts to senior stakeholders, including scientific and executive leadership.
• Influence and coordinate internal teams including Neuroscience, Data Science, Data Engineering, Clinical Operations, Program Management, Business Development, Finance, and Legal to support partnership success.
• Surface risks, dependencies, and tradeoffs early, and lead cross-functional problem-solving to keep partnerships on track.
• Support contract amendments, renewals, and expansion discussions in collaboration with Business Development and Legal teams.
• Own account-level forecasting, revenue planning, and long-term partnership roadmaps, as well as identification and recovery plans if partnership goes off track
• Maintain accurate records of partnership activities, milestones, and expansion opportunities in CRM and other relevant process management systems (Asana).
• Provide leadership with clear, forward-looking insights on partnership health, risks, and growth potential.

What You Will Bring

• Proven experience leading complex client engagements with C-suite visibility and/or multi-year strategic partnerships with biopharma, biotech, or medical technology organizations.
• Exceptional ability to synthesize and communicate complex scientific and technical concepts to diverse audiences, including senior executives with executive-ready narratives.
• 6+ years of experience in consulting, alliance management, or strategic partnerships in the biopharmaceutical industry.
• Strong understanding of the pharmaceutical industry, including clinical development, clinical trial execution, commercial launch strategy and execution, and the use of real-world data across the product lifecycle.
• Demonstrated ability to operate autonomously in a fast-paced startup environment, balancing strategic thinking with hands-on execution.
• Strong executive presence, with the ability to lead meetings, prepare relevant materials tactically, drive alignment, and influence decision-making across organizations.
• Exceptional written and verbal communication skills, including experience developing executive-ready presentations and strategic materials.
• Advanced technical degree (PhD, MD, or Master’s) in neuroscience, biomedical engineering, or a related field, or business degree (MBA) preferred.
• Experience partnering with legal, finance, and operations teams on contract execution, renewals, and scope changes.
• Familiarity with CRM tools and experience managing account-level metrics and forecasts.
• Willingness to travel for customer engagements and internal meetings as needed, typically quarterly.

The base salary range for this role is determined based on past experience, specific skills and qualifications. The base salary is one component of the total compensation package, which includes equity, PTO and other benefits.

At Beacon, we've found that cultural and scientific impact is driven most by those that lead by example. As such, we're always seeking new contributors whose work demonstrates an avid curiosity, a bias towards simplicity, an eye for composability, a self-service mindset, and - most of all - a deep empathy towards colleagues, stakeholders, users, and patients. We believe a diverse team builds more robust systems and achieves higher impact.