
Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.

Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.
About Grafton Sciences We’re building AI systems with general physical ability — the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step towards building superintelligence. With deep technical roots and real-world progress at scale (e.g., a $42M NIH project), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end-to-end, and helping build a capability the world has never had before.
About The Role We’re always looking for individuals who bring world-class ability in engineering, science, research, or operations — even if their background doesn’t fit neatly into one of our listed roles.
If you’re exceptional at building intelligent systems, designing robust physical workflows, creating powerful engineering tools, or inventing new ways for AI to interact with the world, we want to hear from you. We hire people who make the entire organization better — technically, creatively, and operationally.
In this role, you’ll define a scope of work that aligns your strengths with the frontier problems we’re solving. You may work across robotics, AI/ML, digital twins, simulation, agent systems, automation, operations, infrastructure, or entirely new domains we haven’t yet explored.
Responsibilities (Examples) Your work may include (but is not limited to):
Qualifications