
Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.

Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.
About Grafton Sciences Grafton Sciences is building physical superintelligence — autonomous systems that can experiment, reason, and make discoveries in the physical world. Backed by $42.5M from ARPA-H, we’re designing autonomous laboratories that learn through interaction, not imitation. If you want to help invent the future of discovery itself, this is the place.
About The Role We’re always looking for individuals who bring world-class ability in engineering, science, research, or operations — even if their background doesn’t fit neatly into one of our listed roles.
If you’re exceptional at building intelligent systems, designing robust physical workflows, creating powerful engineering tools, or inventing new ways for AI to interact with the world, we want to hear from you. We hire people who make the entire organization better — technically, creatively, and operationally.
In this role, you’ll define a scope of work that aligns your strengths with the frontier problems we’re solving. You may work across robotics, AI/ML, digital twins, simulation, agent systems, automation, operations, infrastructure, or entirely new domains we haven’t yet explored.
Responsibilities (Examples) Your work may include (but is not limited to):
Qualifications