About BiomeSense

BiomeSense is a pioneering life sciences startup focused on harnessing the power of the gut microbiome to revolutionize personalized medicine. With our breakthrough technologies GutLab and MetaBiome, we are setting new standards in microbiome data analysis and interpretation, enabling unprecedented insights to understand & leverage the microbiome for human health. We partner with leading institutions and researchers including UCSF, UCSD, NIH, and the University of Chicago, and are backed by investors such as LabCorp Ventures, Bluestein Ventures, Seerave Foundation, and Emil Capital Partners.

Role Summary

We are looking for a 𝗗𝗶𝗿𝗲𝗰𝘁𝗼𝗿 𝗼𝗳 𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴 to join our leadership team and take full ownership of the technical development, integrity, and scaling of our GutLab at-home sampling technology. This position offers a unique opportunity to combine hands-on engineering expertise with strategic leadership in a fast-paced, high-intensity environment. You will step directly into on-going hardware development and own the complete hardware lifecycle for both existing GutLabs and a new generation build. Key functions include system architecture and subsystem integration, resourcing, manufacturing, validation, and deployment readiness for a product with a large and complex Bill of Materials (BOM).

You will be the final technical authority for system performance, fleet stability, and next generation production. Success in this role requires equal strength in hands-on engineering depth, structured validation rigor, disciplined production planning, and team leadership. You'll combine operational precision with strategic judgment, ensuring the GutLab platform performs reliably in the field and scales efficiently into manufacturing. If you're ready to lead from the front and build with us, we'd love to talk!

𝗞𝗲𝘆 𝗥𝗲𝘀𝗽𝗼𝗻𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝗶𝗲𝘀

• 𝗦𝘆𝘀𝘁𝗲𝗺 𝗢𝘄𝗻𝗲𝗿𝘀𝗵𝗶𝗽 & 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁: Own GutLab architecture (electromechanical and fluidic components); Lead design, testing, and refinement, utilizing your expertise in CAD, prototyping, and manufacturing to deliver high-quality hardware solutions

• 𝗩𝗮𝗹𝗶𝗱𝗮𝘁𝗶𝗼𝗻 & 𝗗𝗲𝗽𝗹𝗼𝘆𝗺𝗲𝗻𝘁 𝗥𝗲𝗮𝗱𝗶𝗻𝗲𝘀𝘀: Own validation framework, pass/fail gates, documentation control and traceability across revisions, firmware, and field performance. Lead field troubleshooting, diagnostics, and closed-loop fixes to eliminate systemic failure modes

• 𝗘𝗻𝗱-𝘁𝗼-𝗘𝗻𝗱 𝗘𝘅𝗲𝗰𝘂𝘁𝗶𝗼𝗻: Drive high standards for quality and performance. Manage all aspects of hardware development, including procurement, manufacturing transfer, sustaining engineering, and operations setup

• 𝗠𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴 𝗦𝗰𝗮𝗹𝗲-𝗨𝗽: Drive DFM, design freeze, pilot builds, supplier alignment, cost targets, and manufacturing strategy + execution for the new generation of GutLabs

• 𝗧𝗲𝗮𝗺 𝗟𝗲𝗮𝗱𝗲𝗿𝘀𝗵𝗶𝗽: Recruit, mentor, and lead a high-performing hardware team to align resources, timelines, and execution to production milestones in support of commercial goals

• 𝗦𝘁𝗿𝗮𝘁𝗲𝗴𝗶𝗰 𝗣𝗿𝗼𝗯𝗹𝗲𝗺 𝗦𝗼𝗹𝘃𝗶𝗻𝗴: Address complex procurement challenges such as fluid tariff issues and supply chain constraints while identifying cost-effective solutions

• 𝗖𝗿𝗼𝘀𝘀-𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗖𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗶𝗼𝗻: Partner with other leaders to align hardware development with broader company strategy and goals

𝗤𝘂𝗮𝗹𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀

• 8+ years' experience in hardware development and/or manufacturing for complex electromechanical systems

• Deep proficiency with complex CAD assemblies, tolerance analysis, prototyping, testing methodologies, and manufacturing processes

• Demonstrated ownership of full product lifecycle – from concept to production

• Experience leading manufacturing transfer and production scale-up

• Proven ability to build and manage technical teams

• Strong systems-level troubleshooting capability across mechanical, fluidic, and electronic domains

• Structured, decisive, and execution-oriented with high accountability

• A strategic thinker who thrives under pressure in fast-paced environments

𝗔𝗯𝗼𝘂𝘁 𝗬𝗼𝘂

You are an experienced engineer who thrives in high-stakes environments where innovation meets execution. You're equally comfortable rolling up your sleeves for hands-on work – whether it's CAD design or testing – and stepping back to set strategy or solve complex procurement issues. If you're ready to take on a leadership role that combines technical expertise with strategic vision in a fast-moving startup environment, we want to hear from you!

𝗖𝗼𝗺𝗽𝗲𝗻𝘀𝗮𝘁𝗶𝗼𝗻

• Salary: $150K – $200K

• Equity: 0.25% – 0.5% stock options

• Full benefits suite including health coverage, PTO, and parental leave