GrittGene Therapeutics

GrittGene Therapeutics is a biotechnology research company focused on curing Myotonic Dystrophy Type 2 using advanced technologies like CRISPR and Artificial Intelligence. Their interdisciplinary approach allows them to leverage a wide range of expertise and collaborations, aiming to provide a comprehensive cure rather than just alleviating symptoms. With a commitment to serving DM patients, GrittGene operates globally, offering diagnostic solutions and developing next-generation treatments through a collaborative platform that combines knowledge, experience, and innovative technologies.

Artificial IntelligenceCRISPRDrug DiscoveryGene TherapyMyotonic Dystrophygrittgene.com

GrittGene Therapeutics

Artificial IntelligenceCRISPRDrug DiscoveryGene TherapyMyotonic Dystrophygrittgene.com

HQGlendale, US

Team Size9

Open JobsUnknown

Total Funding-

Latest FundraiseUnknown

Join the Team

Developmental / Stem Cell biologist

On-SitePasadena, CA, US

On-Site • Pasadena, CA, US

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Part-timeAmsterdam, NL

Part-time • Amsterdam, NL

Job Title: Developmental / Stem Cell biologist

Location: Pasadena, CA

Type: Contract with potential to turn into full-time

Position Summary:

We are seeking a highly motivated Developmental / Stem Cell biologist with expertise in iPSC-derived and MSC derived cell models, with hands on experience of working with key signaling pathways to differentiate stem cells into germ cell lines and subsequent tissue specific organoids and cell types. The ideal candidate will play a key role in developing and validating disease-relevant cellular models, advancing our work in cell therapy and beyond.

Key Responsibilities

Generate, culture, and characterize human iPSC-derived cell lines relevant to neuromuscular and other developmental systems.
Perform cell phenotyping using flow cytometry, immunocytochemistry (ICC), and related imaging-based assays.
Design and execute experiments to assess differentiation efficiency, functional maturity, and molecular signatures.
Collaborate closely with molecular biology and omics teams to integrate cellular data into multi-omics pipelines.
Maintain detailed documentation and contribute to standard operating procedures (SOPs).
Present findings in internal reviews and scientific meetings.

Qualifications

PhD in Developmental Biology, Cell Biology, Regenerative Medicine, Neuroscience, or related fields.
Demonstrated experience in human and mouse stem cell culture, differentiation, and characterization.
Hands-on expertise with flow cytometry, immunocytochemistry (ICC), and cell phenotyping assays.
Strong understanding of developmental and cellular pathways, including cell fate and lineage specification.
Excellent analytical, troubleshooting, and communication skills.
Experience with omics integration, high-content imaging, or CRISPR-based approaches is a plus.

The Company:

GrittGene Therapeutics is a start-up company at the R&D preclinical stage aimed at the development of treatment for DM, particularly DM2. We are building a diverse team of highly motivated professionals from various fields of science and technology. We are building a diverse, interdisciplinary team of dreamers and doers. We’re looking for fellow visionaries hungry for real impact in reimagining every facet of how we cure disease.