About Us At Matterworks we are building AI tools to extract insights from the ever-growing corpora of biological data and to unlock opportunities in therapeutic discovery, development, and manufacturing. We are building large-scale deep learning models of biological data to predict the phenotype and behavior of biological systems.

Position Overview Matterworks is seeking a Data Manager (Bioinformatics / Cheminformatics) to build our data management practice, owning the strategy, processes, and day-to-day execution that turn complex, messy chemical and biological datasets into high-quality, well-governed training corpora and product-ready data assets.

You’ll be the connective tissue between applied science, AI, product, and our data platform/engineering team helping to answer what data is most valuable, how do we onboard it quickly, and how do we keep it consistently high quality over time.

This role will start as an individual contributor with end-to-end ownership, with a growth path to leading a function as we scale.

Key Responsibilities

• Data Strategy & E2E Ownership: Partner with scientific, ML, and product stakeholders to define a data roadmap: which datasets move the needle, which should be refreshed, and what “good enough” looks like for each use case. Establish clear success metrics for onboarding speed, dataset quality, and downstream usability (e.g., fewer training/data failures, higher match rates, better coverage, higher-confidence labels).
• Dataset Sourcing, Discovery, and Intake: Proactively scout and integrate public and client datasets, plus relevant literature and reference materials, to keep our corpora current and comprehensive. Design a repeatable dataset intake workflow including provenance, source tracking, and refresh cadence.

About You

• 6+ years of demonstrated experience owning scientific data work end-to-end (curation, standardization, QC, documentation, governance) in bioinformatics, cheminformatics, computational biology, scientific data engineering, or related roles.

Working at Matterworks Given the cross-disciplinary and innovative nature of our work, effective collaboration and communication are critical to our progress. We operate in a flexible hybrid model that accommodates both fully remote team members and those who work full-time from our Somerville, MA office. While some positions may require regular in-person presence for hands-on work or local collaboration, many roles can be performed remotely with team members distributed across various locations.

Compensation And Benefits Matterworks offers a competitive base salary, stock options, and benefits (health & dental, vision, long- and short-term disability, life insurance, 401k with company match). Employees enjoy a flexible work & unlimited time away policy, commuter benefits and parking, regular team meals and outings, and company support for continued education/coursework and conference participation.

Matterworks, Inc. is an equal opportunity employer. All candidates for employment at Matterworks are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other category protected by law.