
Prenosis enables rapid, biology-driven diagnosis and precision therapy in acute care to improve patient outcomes. The company uses its Immunix platform, combining AI and machine learning with biomarker and clinical data to generate real-time immune-response insights and deliver diagnostics and treatment guidance. Its Sepsis ImmunoScore is an FDA-authorized AI diagnostic for sepsis and is deployed through hospital workflows and EMR integrations. Prenosis operates as a B2B SaaS provider to healthcare systems and providers, leveraging a growing clinical biobank to refine models. The platform targets acute care settings where fast decisioning and integration with electronic medical records are critical.

Prenosis enables rapid, biology-driven diagnosis and precision therapy in acute care to improve patient outcomes. The company uses its Immunix platform, combining AI and machine learning with biomarker and clinical data to generate real-time immune-response insights and deliver diagnostics and treatment guidance. Its Sepsis ImmunoScore is an FDA-authorized AI diagnostic for sepsis and is deployed through hospital workflows and EMR integrations. Prenosis operates as a B2B SaaS provider to healthcare systems and providers, leveraging a growing clinical biobank to refine models. The platform targets acute care settings where fast decisioning and integration with electronic medical records are critical.
Headquarters & Focus: Chicago-based AI healthcare company focused on acute care precision medicine
Flagship product: Sepsis ImmunoScore — FDA De Novo–authorized AI diagnostic for sepsis
Platform: Immunix — biomarker + clinical-data platform and biobank for rapid immune-response insights
Business model: B2B SaaS to healthcare systems with EMR integrations
Recent financing: $20M Series A announced Jan 29, 2026 (led by PACE Healthcare Capital) and $20M BARDA contract
| Company |
|---|
Acute care diagnosis and precision therapy, especially sepsis detection and outcome prediction
2014
Biotechnology Research
$20M
Company announced a $20M Series A and a $20M BARDA contract
Listed as most recent Crunchbase funding event in 2023
“PACE Healthcare Capital led Series A; co-investors include UC Investments, UCI Health Ventures, Labcorp Venture Fund, Global Health Investment Corporation, Illinois DCEO, and Carle Health”
About Prenosis
Prenosis Inc. is an artificial intelligence company pioneering precision medicine in acute care. Our Immunix™ precision medicine platform drives the development of precision products and enables real-time delivery of optimal therapy. We've created and validated the first FDA-authorized AI biomarker for sepsis, the Sepsis ImmunoScore™.
At Prenosis, we:
Our staff collectively defined these corporate values to demonstrate how our teams contribute to meaningful and authentic change in U.S. healthcare. We value our diverse talent, strive to foster a culture of continuous learning, and aim to maintain a feeling of belonging and shared sense of purpose.
Prenosis is headquartered in Chicago Illinois and generally operates on Central Time Zone.
We are seeking a Contract Specialist to join our growing team. The Contract Specialist is responsible for managing, preparing, reviewing, and analyzing contracts and procurement agreements for an organization. This role requires a solid understanding of legal terminology, negotiation skills, and a keen eye for detail to ensure compliance with all applicable laws and regulations. The Contract Specialists work closely with various departments to facilitate clear and enforceable contracts, mitigate risks, and support the organization’s strategic goals.
Responsibilities
Expected frequency and duration of travel: None, except for potential semiannual company meetings
Qualifications and Experience
Required:
What We Offer
Prenosis is an Equal Opportunity Employer
Must be eligible to work in the US without sponsorship