
WhiteLab Genomics provides an AI-driven platform that speeds discovery and design of genomic therapies, reducing time and experimental workload. It combines graph knowledge technology, machine learning, and advanced computational biology to perform in-silico design and optimization of vectors, payloads, genotoxicity assessment, and experimental protocols. The platform supports modalities including AAV, lentiviral, and nanoparticle delivery and is used by biopharmaceutical companies and research institutions. WhiteLab's tools integrate into genomic R&D workflows to de-risk early development and accelerate candidate selection for downstream preclinical testing.

WhiteLab Genomics provides an AI-driven platform that speeds discovery and design of genomic therapies, reducing time and experimental workload. It combines graph knowledge technology, machine learning, and advanced computational biology to perform in-silico design and optimization of vectors, payloads, genotoxicity assessment, and experimental protocols. The platform supports modalities including AAV, lentiviral, and nanoparticle delivery and is used by biopharmaceutical companies and research institutions. WhiteLab's tools integrate into genomic R&D workflows to de-risk early development and accelerate candidate selection for downstream preclinical testing.
What they do: AI-driven platform (ALFRED AI) for design and optimization of genomic medicines (AAV, lentiviral, non-viral vectors, payloads, bioproduction)
Founded: 2019
Headquarters / presence: Paris, Boston, Montréal
Funding: $10M seed (Sep 12, 2022); pre-seed tied to Y Combinator (Mar 2022)
Investors / partners: Debiopharm Group, Omnes Capital, Y Combinator
Accelerating and de-risking genomic medicine R&D (gene and cell therapy development).
2019
Biotechnology
Pre-seed round associated with Y Combinator
10000000
Seed round announced Sep 12, 2022
“Debiopharm Group and Omnes Capital are lead investors; Y Combinator participated in earlier round”
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Our Computational Biology Team plays a key role in developing prediction and optimization tools for payload design and manufacturing for gene and cell therapy. We analyze complex multi-omic datasets, particulary single-cell RNA-seq and DNA –based assays , to support our research efforts to improve drug design in gene and cell therapy. The Computational Biologist will actively participate to the development of WLG’s In-silico tools, pipelines and models.
As a Computational Biologist, here’s how you will make an impact:
You will:
Provide bioinformatics analyses and contribute to the development of innovative approaches for various research and customer projects in collaboration with the other technical teams
Develop and implement algorithms and statistical methods for the integration, visualization, and interpretation of complex biological datasets, with a strong focus on multi-omic data
Participate and actively collaborate within cross-functional and cross-thematic projects, working under the supervision and guidance of project managers
Support the improvement, design and maintenance of in-house data analysis pipelines and contribute to the integration of new computational methodologies and best practices
Assist in the validation of machine learning solutions for vector and synthetic promoter designs, help advance WhiteLab Genomics’ internal R&D platforms
Contribute to hypothesis generation and experimental design in computational biology
Support internal research projects to advance core scientific methodologies, focusing on the development of methods leveraging multi-omic data to optimize the design of DNA sequences used in cell and gene therapies
Present your findings and discoveries with the WhiteLab Genomics teams, enhancing our collective knowledge and contributing to our overall successWe’re eager to meet you if you
Hold a recent PhD or Master’s degree in bioinformatics, computational biology, biostatistics, or a related field
Have 1–4 years of experience in biological data analysis
Possess strong programming skills in Python or R, with familiarity using bioinformatics toolkits and libraries (e.g. Bioconductor, scikit-learn, Scanpy, Seurat)
Are proficient in the analysis of multi-omic datasets, such as single-cell RNA-seq, ATAC-seq, and other NGS data types
Have a solid foundation in molecular biology and experience working with biological databases and reference resources (e.g., Ensembl, UniProt, NCBI).
Demonstrate a strong understanding of statistical methods for analyzing biological data
Can communicate complex scientific concepts clearly with internal and external stakeholders and work effectively in a collaborative research environment.
Nice to have