About Genesis Molecular AI
Genesis Molecular AI unifies cutting edge molecular machine learning with rigorous physics to discover novel small molecule therapies for severe diseases. Our molecular AI platform, GEMS, combines generative models and high throughput molecular simulation to search chemical space and prioritize compounds with unprecedented speed and accuracy.
We are bringing together a world-class computational team to build out the industry's fastest and most accurate small molecule property predictions, by combining the power of machine learning and physics-based methods.
About The Team
Our computational chemistry team partners with ML researchers, medicinal chemists, and biologists to turn our computational models into real drug candidates for our internal pipeline and our pharma collaborators.
You will join a team led by experienced drug hunters and method developers across statistical mechanics, free energy methods, and computer aided drug design.
About The Role
We are looking for a
binding free energy specialist,
who is comfortable both with the theory necessary to propose new methodological ideas and with coding necessary to implement them. This individual will advance free energy methods across our platform and own their delivery.
You will be the person our teams turn to when they need physics based ranking of tight binders, especially in potency regimes where current models start to flatten out. Your work will directly shape which compounds we make, which ones move forward, and how quickly we discover the best molecules for patients.
This is not a “button pusher” role. You should have a strong understanding of theory and enjoy getting your hands “dirty,” coding up tools and getting them into the hands of project teams.
What You Will Do:
Who You Are:
About Genesis Molecular AI
Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.
Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.
