
Helical is focused on providing open-source bio foundation models, particularly in the realm of single-cell analysis, enabling scientists to leverage advanced AI tools for their research. Their platform offers a community-driven approach, allowing users to fine-tune and integrate these models into their workflows, thereby enhancing research capabilities in the biological sciences. With a commitment to accessibility and collaboration, Helical positions itself as a key player in the AI for bio sector, catering to researchers and developers looking for innovative solutions.

Helical is focused on providing open-source bio foundation models, particularly in the realm of single-cell analysis, enabling scientists to leverage advanced AI tools for their research. Their platform offers a community-driven approach, allowing users to fine-tune and integrate these models into their workflows, thereby enhancing research capabilities in the biological sciences. With a commitment to accessibility and collaboration, Helical positions itself as a key player in the AI for bio sector, catering to researchers and developers looking for innovative solutions.
What they do: Platform for Bio Foundation Models enabling in-silico experiments for drug discovery and R&D
HQ: Luxembourg
Stage / funding: Seed (closed Jun 28, 2024)
Founders: Mathieu Klop; Maxime Allard; Rick Schneider
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Drug discovery and pharmaceutical R&D using AI-driven in-silico experiments
2024
Biotechnology Research
Reported seed round with seven investors
“Has participation from early-stage investors and angel/backer set including Frst and named investors”
Drug discovery still relies on wet labs: slow, expensive, and constrained by physical trial-and-error. Helical is changing that.
We build the application layer that makes Bio Foundation Models usable in real-world drug discovery, enabling pharma and biotech teams to run millions of virtual experiments in days, not years. Today, leading global pharma companies already use Helical, and we’re at the start of a highly ambitious growth journey.
We’re a founder-led, talent-dense team building a category-defining company from Europe. We care deeply about the quality of our work, move fast, and expect ownership. If you’re excited by complexity, real responsibility, and shaping how a company actually operates as it scales, you’ll feel at home here.
About the role
We’re hiring a Chief of Staff to play a pivotal role in how Helical scales.
This is a high-leverage operating role at the heart of the company, designed for someone who wants real responsibility and meaningful influence over how a category-defining business actually runs. It’s a role for an operator who thrives in complexity, enjoys being close to the action, and wants to shape the way a company executes as it grows.
You’ll work directly with the CEO and leadership team to:
This role exists to amplify the CEO’s impact, freeing him to focus on the work only he can do, while you ensure the business continues to move forward with speed, clarity, and momentum.
If done well, this will be one of the most impactful roles at Helical.
What you’ll do
In practice, you will:
Who we’re looking for
We’re looking for a high-judgement operator who wants to sit close to the centre of a scaling company and take real ownership over how it runs.
You’re someone who has already experienced the reality of growth, where priorities compete, information is imperfect, and progress depends on clarity, follow-through, and good judgement more than formal process.
You bring:
More than a specific title or background, we’re looking for someone who:
Domain experience
Experience in biotech, life sciences, deep tech, or AI is a strong plus — but not required. Curiosity, respect for technical depth, and the ability to ask good questions matter more than prior domain knowledge.
What success looks like (6–12 Months)