
Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.

Grafton Sciences is focused on building physical superintelligence to accelerate scientific discovery. Their mission is to create systems capable of autonomous scientific discovery, utilizing tools that expand our capabilities. They are developing an at-home early detection platform for cancer, leveraging advances in synthetic biology and nanotechnology. With a $42.5 million contract from ARPA-H, Grafton aims to detect over 48 tumors at Stage I, representing a significant portion of the global cancer burden. Their approach integrates computational modeling, automated experimentation, and materials engineering, positioning them as leaders in the field of disease detection and scientific innovation.
About Grafton Sciences We’re building AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step toward building superintelligence. With deep technical roots and real-world progress at scale (for example, a $42 million NIH program), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end to end, and helping build a capability the world has never had before.
About The Role We’re looking for a Chief of Staff who operates as an extension of the CEO—someone who removes obstacles, drives clarity, and ensures the company is moving fast. This is a high-leverage, high-trust role for an individual with strong technical intuition, exceptional execution ability and a founder-type mindset.
Qualifications
Above all, we look for candidates who can demonstrate world-class excellence