We are currently recruiting for a HT Analytical Associate Scientist I to join our team in Alderley Park.

Role: HT Analytical Associate Scientist I

Role Type: 6 month fixed term contract

Hours: Full time, 37.5 hours per week

Start Date: Monday 29th September 2025

Salary: Competitive, with excellent benefits package

Location:

Alderley Park

, Macclesfield, SK10 4TG

Our Company

Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines. With state-of-the-art facilities and technical expertise, we specialise in in vitro and in silico ADME-Tox services, providing a wide range of assays tailored to our client’s needs. This includes in vitro screening to support discovery projects, regulatory studies to support preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on efficiencies and innovation.

Our Alderley Park site is set in the heart of Cheshire surrounded by stunning 400-acre estate, open green spaces, sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, and Shropshire. Easy access to public transport.

Cyprotex is part of the Evotec Group, a global leader in research. With state-of-the-art facilities and technical expertise, we provide innovative and bespoke assurance tailored to each of our client’s needs. As a member of Physical Chemistry, you will support the team in delivering high-quality aqueous solubility, lipophilicity, pKa, aqueous chemical stability, and matrix-binding data to our clients, supporting their drug discovery activities.

Key Responsibilities

• MS/MS compound optimisation and LC method optimisation for high volumes of compounds using automated tools and established processes
• Co-ordination of in vitro assay LC-MS/MS support
• Troubleshooting and system maintenance and co-ordination of engineer visits
• Contributing to our Quality System via preparation of SOPs
• Laboratory support including ordering, equipment calibration and validation
• To aid in the development of new methods and improvements to the current analytical capabilities at Cyprotex

Additional Responsibilities may include

• Interacting with our Information Systems Team to design and implement automation and data processing tools
• To aid in the development of new methods and improvements to the current analytical capabilities at Cyprotex

Skills & Competencies (essential)

• Minimum BSc (or equivalent) in relevant scientific discipline covering chemistry.
• Extensive computer literacy including the use of Microsoft Office.
• Produce accurate documentation and report all analytical activities and results in a clear and coherent manner, maintaining the highest standards of quality and compliance, with a high level of attention to detail and the ability to work without close supervision.
• Highly motivated team player with a high level of dedication.
• Ability to learn new techniques and processes at a fast pace.
• Communicate effectively between departments and follow detailed instructions.
• Plan, schedule and carry out your work effectively for successful project completion.

Preferred but not essential

• Experience in working with LC-MS/MS techniques in support of pre-clinical small molecule assays.
• Experience with MassLynx™, Analyst™ or other Mass Spectrometry data-acquisition software packages.
• A wider knowledge of analytical support in drug discovery/development.
• A knowledge of DMPK/ADME assays within drug discovery.
• The ability to perform routine maintenance on LC-MS/MS equipment

What we can offer you in return

We offer a competitive salary and benefits package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.

Onsite Facilities

• The company pays for secure onsite parking
• Restaurant, Café, and Gastro pub
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service.

Interested?

Apply NOW – please upload your up-to-date CV and cover letter to Workday via our careers page

***Closing date for applications is Sunday 14th September 2025, however we may close earlier depending on the response we receive***

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.