
Zeta Surgical is redefining the standard of care for image-guided surgery. Its cutting-edge navigation and robotics platform applies advanced AI to enable high-accuracy image guidance across any point-of-care in minutes, unlocking a new era of less invasive and more effective targeted therapies. The Zeta Surgical Cranial Navigation System is cleared by the FDA and commercially available in the US.

Zeta Surgical is redefining the standard of care for image-guided surgery. Its cutting-edge navigation and robotics platform applies advanced AI to enable high-accuracy image guidance across any point-of-care in minutes, unlocking a new era of less invasive and more effective targeted therapies. The Zeta Surgical Cranial Navigation System is cleared by the FDA and commercially available in the US.
Product: ZETA Cranial Navigation System — AI-driven, frameless neuronavigation with markerless registration and sub-millimeter accuracy
FDA status: FDA 510(k) clearance and commercially available in the US
Headquarters: Boston, Massachusetts
Founded: 2018
Employees: 9
Total reported funding: USD 13,930,000
Image-guided neurosurgery/navigation for cranial procedures (ventriculostomy, brain biopsy, TMS targeting, tumor procedures).
2018
Medical devices / Surgical navigation
USD 5,200,000
Seed round reported in March 2022; press coverage cites ~USD 5.2M led by Innospark Ventures.
USD 250,000
Pre-seed participation reported including Y Combinator and Plug and Play.
Company databases list a Series A entry dated 2025-01-21.