
Synplexity helps research teams accelerate biological discovery by generating broad, high-quality training datasets through large-scale mutational scanning and multiplexed gene synthesis. The company combines AI-driven sequence design with high-throughput DNA synthesis and multiplexed screening to produce broad and deep variant libraries tailored for parallel screening. Synplexity operates as a B2B biotechnology platform serving research labs and biotechs working on industrial enzymes, therapeutics, and discovery programs. Core technologies include machine learning for sequence design, large-scale DNA synthesis workflows, and multiplexed screening integrations. The platform targets organizations aiming to scale experiments and improve model-driven design cycles.

Synplexity helps research teams accelerate biological discovery by generating broad, high-quality training datasets through large-scale mutational scanning and multiplexed gene synthesis. The company combines AI-driven sequence design with high-throughput DNA synthesis and multiplexed screening to produce broad and deep variant libraries tailored for parallel screening. Synplexity operates as a B2B biotechnology platform serving research labs and biotechs working on industrial enzymes, therapeutics, and discovery programs. Core technologies include machine learning for sequence design, large-scale DNA synthesis workflows, and multiplexed screening integrations. The platform targets organizations aiming to scale experiments and improve model-driven design cycles.
Founded: 2024
Headquarters: Eugene, Oregon, USA
Core offering: Multiplexed gene synthesis and large-scale mutational scanning (NucleoPools™)
Tech & methods: AI-driven sequence design, DropSynth microreactor technology, high-throughput DNA synthesis
Investors (reported): IndieBio, SOSV
Enabling scalable generation of diverse sequence variant data for protein engineering, therapeutics discovery, and industrial enzyme development.
2024
Biotechnology
Reported investors include IndieBio and SOSV.
“IndieBio; SOSV (reported)”