
SirenOpt is a manufacturing intelligence company pioneering a paradigm shift in advanced materials characterization by leveraging cold atmospheric plasma, machine learning, and predictive analytics to non-destructively create multifaceted material fingerprints in real-time. Their core product, PlasmaSens™, enables real-time, non-destructive, multi-property measurement of materials across various manufacturing workflows such as wafer-to-wafer, piece-to-piece, sheet-to-sheet, and roll-to-roll processes. This technology addresses measurement blind spots, accelerating R&D, process optimization, and enhancing product performance and production quality in industries including battery, aerospace, semiconductor, electronics, and more. SirenOpt originated as a spin-out from UC Berkeley and has gained traction through early adoption by Bay Area battery startups, participation in Berkeley SkyDeck Accelerator, and a $6.6M seed funding round in 2024. Their technology expertise includes low-energy plasma control and physics-informed machine learning for advanced process and equipment control, positioning them as a leader in sustainable, smart manufacturing of advanced materials.

SirenOpt is a manufacturing intelligence company pioneering a paradigm shift in advanced materials characterization by leveraging cold atmospheric plasma, machine learning, and predictive analytics to non-destructively create multifaceted material fingerprints in real-time. Their core product, PlasmaSens™, enables real-time, non-destructive, multi-property measurement of materials across various manufacturing workflows such as wafer-to-wafer, piece-to-piece, sheet-to-sheet, and roll-to-roll processes. This technology addresses measurement blind spots, accelerating R&D, process optimization, and enhancing product performance and production quality in industries including battery, aerospace, semiconductor, electronics, and more. SirenOpt originated as a spin-out from UC Berkeley and has gained traction through early adoption by Bay Area battery startups, participation in Berkeley SkyDeck Accelerator, and a $6.6M seed funding round in 2024. Their technology expertise includes low-energy plasma control and physics-informed machine learning for advanced process and equipment control, positioning them as a leader in sustainable, smart manufacturing of advanced materials.
What they do: Real-time, non-destructive materials characterization using cold atmospheric plasma + ML
Flagship product: PlasmaSens
Founded / origin: 2022 spin-out from UC Berkeley Chemical Engineering
Notable funding: $6.6M seed (Jul 2024) with additional strategic investment activity
Headquarters: Oakland, California
Inline and offline materials characterization and manufacturing intelligence for advanced materials used in semiconductors, batteries, electronics, and aerospace.
2022
Renewable Energy Semiconductor Manufacturing
6600000
Announced seed round with participation from multiple VC and strategic investors.
2400000
Listed as a grant in some records.
Company announced a strategic investment to accelerate commercialization.
“Access Industries; Berkeley SkyDeck Fund; California Energy Commission; Climate Capital; Climate Club; Courtyard Ventures; Hitachi Ventures; Impact Science Ventures; InMotion Ventures; Union Labs Ventures; Visionaries Tomorrow; Voyager Ventures; Wireframe Ventures”
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