
Simulations Plus is a leading provider of modeling and simulation software and consulting services that support drug discovery, clinical development research, and regulatory submissions. The company offers a broad portfolio of validated AI/machine learning, quantitative systems pharmacology/toxicology (QSP/QST), physiologically based pharmacokinetics (PBPK), and population PK/PD modeling software for both novice and expert users. Their flagship products include GastroPlus, ADMET Predictor, MonolixSuite, and DILIsym, among others. With over 25 years of experience, Simulations Plus serves more than 280 clients worldwide, including 18 of the top 20 pharmaceutical companies, providing solutions that accelerate and reduce the costs of R&D while improving patient outcomes. The company also offers expert consulting services and training programs to complement its software offerings, positioning itself as a thought leader in model-informed drug development globally.

Simulations Plus is a leading provider of modeling and simulation software and consulting services that support drug discovery, clinical development research, and regulatory submissions. The company offers a broad portfolio of validated AI/machine learning, quantitative systems pharmacology/toxicology (QSP/QST), physiologically based pharmacokinetics (PBPK), and population PK/PD modeling software for both novice and expert users. Their flagship products include GastroPlus, ADMET Predictor, MonolixSuite, and DILIsym, among others. With over 25 years of experience, Simulations Plus serves more than 280 clients worldwide, including 18 of the top 20 pharmaceutical companies, providing solutions that accelerate and reduce the costs of R&D while improving patient outcomes. The company also offers expert consulting services and training programs to complement its software offerings, positioning itself as a thought leader in model-informed drug development globally.
Business: Modeling & simulation software and consulting for drug discovery through regulatory submissions
Flagship products: GastroPlus, ADMET Predictor, DILIsym, MonolixSuite
Public status: Public company listed on NASDAQ (SLP)
Founded: 1996
Clients: Serves 280+ clients, including many top pharmaceutical companies
Pharmaceutical modeling & simulation across discovery, development, safety assessment, and regulatory submissions.
1996
Life sciences / Scientific software
Recorded as a grant round led by the FDA.
Recorded as a grant round involving the NIH.
$5.7M
Company completed an initial public offering on this date.
“Company has received government grant funding (FDA, NIH) and is publicly listed on NASDAQ (SLP).”