
Serna Bio is an AI-enabled drug discovery company focused on designing small molecules that target RNA, shifting the drug discovery paradigm from protein to RNA targeting. Their platform leverages synthetic biology, machine learning, and multiplexed screening to rationally design selective small molecules that modulate RNA functions such as translation and splicing, addressing challenging and previously undruggable targets. Key products include Orion, the world's largest dataset of experimentally determined druggable RNA structures; Polaris, a GenAI platform for molecule design; and Ara, an in-cell chemi-transcriptomics screening platform. Serna Bio collaborates with major biotech companies like Bayer and aims to unlock the transcriptome as a drug target, positioning itself as a leader in RNA-targeted therapeutics with a unique tech-bio integrated platform.

Serna Bio is an AI-enabled drug discovery company focused on designing small molecules that target RNA, shifting the drug discovery paradigm from protein to RNA targeting. Their platform leverages synthetic biology, machine learning, and multiplexed screening to rationally design selective small molecules that modulate RNA functions such as translation and splicing, addressing challenging and previously undruggable targets. Key products include Orion, the world's largest dataset of experimentally determined druggable RNA structures; Polaris, a GenAI platform for molecule design; and Ara, an in-cell chemi-transcriptomics screening platform. Serna Bio collaborates with major biotech companies like Bayer and aims to unlock the transcriptome as a drug target, positioning itself as a leader in RNA-targeted therapeutics with a unique tech-bio integrated platform.