
Sail Biomedicines is at the forefront of programmable medicines, leveraging AI and a proprietary bioplatform to create life-changing treatments. Their core technology revolves around Endless RNA (eRNA), a circular RNA that allows for prolonged and programmable protein expression within the body, offering enhanced durability against degradation. Complementing this is their work in programmable nanoparticles, designed using a broad range of natural chemistries for improved deployment and tropism. Sail integrates these technologies with generative AI and rapid prototyping to design novel RNA medicines aimed at treating a spectrum of diseases including autoimmune, metabolic, infectious, and rare diseases.

Sail Biomedicines is at the forefront of programmable medicines, leveraging AI and a proprietary bioplatform to create life-changing treatments. Their core technology revolves around Endless RNA (eRNA), a circular RNA that allows for prolonged and programmable protein expression within the body, offering enhanced durability against degradation. Complementing this is their work in programmable nanoparticles, designed using a broad range of natural chemistries for improved deployment and tropism. Sail integrates these technologies with generative AI and rapid prototyping to design novel RNA medicines aimed at treating a spectrum of diseases including autoimmune, metabolic, infectious, and rare diseases.
Founded: 2017
Headquarters: Cambridge, Massachusetts
Core focus: Therapeutics platform exploring molecular relationships between bacterial, botanical, and human cells
Recent notable financing: Series C $123M (Aug 16, 2022)
Acquisition / merger activity: Acquired Kintai Therapeutics (2020); merged into/acquired by Sail Biomedicines (announced Oct 19, 2023)
Therapeutics discovery and delivery leveraging molecular interactions across bacterial, botanical, and human cells
2017
Biotechnology / Therapeutics
$123,000,000
Series C announced Aug 16, 2022
“Flagship Pioneering, Alexandria Venture Investments, Samsung Life Science Fund, Mayo Clinic, Longevity Vision Fund, Qatar Investment Authority (reported investors across rounds)”