
Proteinea is a biotechnology company specializing in the rational engineering of antibody Fc domains using proprietary AI models and computational tools. Their platform enables the design of next-generation antibodies with enhanced efficacy, safety, and convenience by tuning immune function, improving half-life, and targeting biodistribution. Proteinea integrates manufacturability, stability, pharmacokinetics, and delivery considerations into their modular Fc scaffolds to reduce downstream failure and accelerate therapeutic development. Their approach combines AI-driven prediction with lean experimental validation to efficiently translate computational designs into biological reality, positioning them as innovators in biologics engineering for life-threatening diseases.

Proteinea is a biotechnology company specializing in the rational engineering of antibody Fc domains using proprietary AI models and computational tools. Their platform enables the design of next-generation antibodies with enhanced efficacy, safety, and convenience by tuning immune function, improving half-life, and targeting biodistribution. Proteinea integrates manufacturability, stability, pharmacokinetics, and delivery considerations into their modular Fc scaffolds to reduce downstream failure and accelerate therapeutic development. Their approach combines AI-driven prediction with lean experimental validation to efficiently translate computational designs into biological reality, positioning them as innovators in biologics engineering for life-threatening diseases.
Headquarters: Cambridge / Boston, MA
Founded: 2020
Core focus: AI-driven antibody Fc and protein engineering
Total disclosed funding: USD 7,490,000
Notable technologies: RaGene (AI gene/codon optimization)
| Company |
|---|
Biologics engineering—designing next-generation antibodies and sequence optimization to improve therapeutic properties and manufacturability.
2020
Biotechnology
USD 4,700,000
USD 2,200,000
USD 500,000
USD 90,000
“500 Global; Core Vision Investments; Den Venture Capital; ICLUB VC; IndieBio; Jedar Capital; SOSV; Sadu Capital; Sawari Ventures; Shorooq Partners; Sukna Ventures; TA Ventures; UI Investments”