
Peptilogics is a clinical-stage biotechnology company revolutionizing peptide therapeutics discovery by combining peptide biology with machine learning and high-performance computing. Their AI-driven platform enables in silico predictive design of novel peptides optimized for binding, selectivity, safety, and drug-like properties, targeting serious and life-threatening diseases with high unmet medical needs. Founded in 2013, Peptilogics advances a pipeline including PLG0206, a broad-spectrum anti-infective peptide therapeutic. The company integrates peptide R&D, proprietary AI technologies, and computational power to unlock new chemical space and accelerate drug discovery at unprecedented scale and pace, positioning itself as a leader in peptide drug design innovation.

Peptilogics is a clinical-stage biotechnology company revolutionizing peptide therapeutics discovery by combining peptide biology with machine learning and high-performance computing. Their AI-driven platform enables in silico predictive design of novel peptides optimized for binding, selectivity, safety, and drug-like properties, targeting serious and life-threatening diseases with high unmet medical needs. Founded in 2013, Peptilogics advances a pipeline including PLG0206, a broad-spectrum anti-infective peptide therapeutic. The company integrates peptide R&D, proprietary AI technologies, and computational power to unlock new chemical space and accelerate drug discovery at unprecedented scale and pace, positioning itself as a leader in peptide drug design innovation.
Stage: Clinical-stage (lead candidate PLG0206)
Founded: 2013
Headquarters: Pittsburgh, Pennsylvania
Core tech: Computational/AI-driven peptide design
Notable investors: Founders Fund; Presight Capital; Peter Thiel; CARB‑X; Cystic Fibrosis Foundation
Infectious disease / anti-biofilm therapeutics; peptide therapeutics discovery
2013
Research Services
5.5M USD
78M USD
“Backed by venture investors including Founders Fund, Presight Capital and entities associated with Peter Thiel; also supported by mission/non-dilutive funders such as CARB‑X and the Cystic Fibrosis Foundation”
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