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NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism…

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism…
Mission: Extend human healthspan by epigenetically reprogramming aged cells to restore youthful function
Platform: Discovery Engine combining high-throughput functional genomics, single-cell multi‑omics, pooled perturbation screening, and machine learning
Funding (disclosed): $170M across a $40M Series A (May 2023) and $130M Series B (May 2025)
Notable founders: Brian Armstrong, Blake Byers, Jacob C. Kimmel (also listed: Greg Johnson)
Early programs: Liver, immune, and vascular systems
Team size (reported): 34 (as of May 2025)
Age-related disease and loss of cellular function due to epigenetic aging
2022
Biotechnology Research
$40M
Investors included Dimension Capital, Founders Fund, Kleiner Perkins, with participation from angels such as Eric Schmidt, Elad Gil, Garry Tan, and Fred Ehrsam.
$130M
Series B included new investors (e.g., Nat Friedman & Daniel Gross, Khosla Ventures, Human Capital, Valor Equity Partners) alongside returning backers such as Dimension Capital and Founders Fund and multiple angel investors.
$45M
Described as additional financing including participation from Eli Lilly & Company, Duke Management Company, Section 32, and others.
“Backed by top-tier venture firms (Kleiner Perkins, Founders Fund, Dimension Capital, Khosla Ventures), strategic/corporate investors including Eli Lilly, university management company participation, and numerous prominent angel investors.”
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