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Nested Therapeutics is a precision oncology company focused on discovering and developing small-molecule drugs that target overlooked driver mutations in cancer. Utilizing a unique drug discovery…

Nested Therapeutics is a precision oncology company focused on discovering and developing small-molecule drugs that target overlooked driver mutations in cancer. Utilizing a unique drug discovery…
Founded: 2021
Headquarters: Cambridge, Massachusetts
Therapeutic focus: Precision oncology — mutation‑selective small molecules
Lead program: NST-628 (brain‑penetrant pan‑RAF/MEK molecular glue, Phase 1)
Total funding: USD 125,000,000
Cancer — mutation‑defined/cryptic pockets for targeted small‑molecule therapeutics
2021
Biotechnology
Early/founder funding tied to Versant Ventures
USD 90,000,000
Series A led by Goldman Sachs Asset Management as part of $125M total financing announced at launch
“Includes participation from Foresite Capital, Avidity Partners, Cowen Healthcare Investments and Section 32”
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